Parasitology: Platyhelminths Flashcards

1
Q

General Characteristics of Phylum Platyhelmithes

A
  • flat mostly
  • hermaphrodites (have both sex organs)
  • definitive host diagnosis– eggs
  • at least 1 intermediate host (diagnosis is difficult)
  • tapeworms and flukes
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2
Q

Which worms are associated with Class Cestoda?

A

Tapeworms

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3
Q

Characteristics of tapeworms

A
  • segmented, often long
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4
Q

Where should we generally assume Cestodas are

A

in small intestine

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5
Q

T/F: tapeworms have an intestine

A

false; they do not, and they absorb nutrients across the surface

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6
Q

Tapeworms have at least 1 _____.

A

intermediate host

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7
Q

What are the segments of the Adult Tapeworm

A
  • the scolex
  • the neck
  • Proglottids (segments)
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8
Q

What is the function of the Scolex?

A

the anterior end, has suckers and/or hooks that allow it to attach to gut wall, though they are capable of moving around

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9
Q

What is the importance of the neck in tapeworms?

A

it is the region of cell division, which gives rise to proglottids (segments)
these mature as they move down the chain

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10
Q

What are the Proglottids?

A

oldest segments of the tapeworm, located at the posterior end

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11
Q

Each segment of a tapeworm has at least _____

A

one set of all reproductive organs of both sexes

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12
Q

The segments of tapeworms are classifed as____ or _____

A

immature: fertilization cannot take place, will mature as it moves down the chain

Mature: fertilization can take place here.

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13
Q

A Gravid contains what?

A

fully developed eggs

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14
Q

What is a gravid?

A

a segment of Tapeworm that is full of eggs. Essentially, the uterus full of eggs. As soon as it comes out of the host, it is fully infective

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15
Q

What is the general term for a larval tapeworm?

A

metascestode

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16
Q

What is the general life cycle of tapeworms?

A
  1. Adult tapeworm lays eggs which are passed into environment.
  2. Infective eggs are eaten by the intermediate host.
  3. Metacestode/intermediate host eaten by the definitive host
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17
Q

What are the definitive and intermediate hosts of the family Taeniidae

A

vertebrates

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18
Q

What do the segments of Taeniidae look like?

A

square to rectangular in shape

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19
Q

Which stage is most important for disease and/or ecnomic loss?

A

the larval stage

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20
Q

Why don’t we see Taeniidae eggs in fecal samples

A

Because the eggs are located in the segments (gravid)

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21
Q

For the Family Taeniidae, the definitive host is generally a _____

A

predatory mammal

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22
Q

for the family Taeniidae, the intermediate host is generally a____

A

herbivore or carnivore

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23
Q

what are the two important larval forms of Taeniidae?

A
  • Cystticercus

- Hydatid

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24
Q

What is cysticercus composed of?

A
  • have fluid-filled bladder

- have an inverted, invaginated scolex

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25
Q

1 cysticercus will produce how many adult tapeworms in the definitive host

A

only 1

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26
Q

what is an infection with cysticercus called?

A

cysticercosis

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27
Q

What are some noteworthy taeniid species with canid or felid definitive hosts in the US.

A
  • Taenia pisiformis
  • Taenia taeniaeformis
  • Taenia hydatigena
  • Echinococcus mutilocularis
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28
Q

T. taeniaeformis is a common tapeworm of ____

A

hunting cats

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29
Q

What is the intermediate host of T. taeniaeformis? where are the larvae located?

A
  • rodents

- the liver

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30
Q

What is the definitive host of T. pisiformis?

A

canids

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31
Q

What is the intermediate host of T. pisiformis?

A

rabbits

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32
Q

T/F: if a cat eats a rabbit infected with T. pisiformis, it will get a tape worm.

A

false

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33
Q

Clinical signs of tapeworms

A
  • pretty benign, don’t cause many issues

- no diarrhea, no weight loss

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34
Q

T/F: fecal floats are good at detecting tapeworm eggs

A

false

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35
Q

How do you diagnose tapeworm infections?

A

segment or egg detection

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36
Q

T/F: tapeworm segments can move away from where they were dropped

A

true, to a short distance

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37
Q

how are tapeworm eggs dispersed from the segment?

A

segment dissolves or dries out, and the eggs are released

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38
Q

What is the definitive host of T. hydatigena

A

canids

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39
Q

What is the intermediate host of T. hydatigena

A

wild, domestic ruminants, pigs

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40
Q

Where are the cysticerci attached to in these intermediate hosts? When would these cause concern

A

on the peritoneal membranes; at slaughter of food animals

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41
Q

Why does Echinococcus have a different species name than other tapeworms?

A

its a different kind of tapeworm in its larval stage

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42
Q

Differentiate between Echinococcus spp. and Taenia spp.

A

Echinococcus spp. are much tinier than Taenia spp. (3-6 mm in length

  • the host will have many small tapeworms rather than a few big ones
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43
Q

What is the metacestode stage of Echinococcus spp.

A

the Hydatid cyst.

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44
Q

T/F: Echinococcus spp. are zoonotic

A

true

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45
Q

What is the importance of the hydatid cyst asexual multiplication

A

multiple scoleces are formed, could potentially form thousands of scoleces

46
Q

What are the two types of hydatid cysts?

A
  • multilocular cysts, which continue to bud off new chambers (seen in E. multilocularis)
  • unilocular hydatid cysts, which grows like a balloon as more buds form within it (seen in E. granulosus and others)
47
Q

What is the definitive host of E. multilocularis

A
  • foxes, but sometimes dogs and other canids (and rarely a cat)
48
Q

What are the intermediate hosts of E. multilocularis?

A

small rodents, humans

49
Q

What is the larval stage of E. multilocularis?

A

….. multilocular hydatid cyst

50
Q

What is the clinical importance of E. multilocularis?

A
  • ITS ZOONOTIC (hydatidosis)

- difficult to surgically remove because of invasive growth

51
Q

T/F: Echinococcus multilocularis infection is easy to diagnose in dogs.

A

false, Hard af

52
Q

What type of hydatid cyst do E. granluosus form?

A

unilocular hydatid cyst formed in intermediate hosts

53
Q

What is the definitive host of E. granulosus? the intermediate host?

A

definitive: dogs
Intermediate: sheep

54
Q

Should you expect your sheep guard dog to be infected with E. granulosus?

A

no, your guard dog shouldn’t be eating your sheep

55
Q

Why don’t we worry about E. granulosus in US?

A

we don’t allow for the cycle to be completed. we remove the carcasses of sheep who die. The dogs therefore can’t eat them

56
Q

What are the intermediate and definitive hosts of Taenia saginata?

A

definitive: humans
intermediate: bovines

57
Q

What type of T. saginata larvae are present in the intermediate host? where in the host?

A
  • cysticerci

- the muscles

58
Q

Clinical importance of T. saginata

A
  • causes mild abdominal discomfort
  • occurs worldwide (was less of a problem in US, but prevalence likely rising due to immigrants from endemic areas and contaminated cattle feed)
59
Q

How do you diagnose T. saginata?

A
  • slaughter inspection: check masseter, tongue, heart incised, and other muscle examination
60
Q

How do you treat T. saginata?

A
  • none in cattle

- cysticerci killed by heating to 57 C or freezing to -10 C for 10 days

61
Q

What are the definitive and intermediate hosts of Taenia solium?

A

Definitive: Humans

Intermediate: porcine

62
Q

What are the concerns regarding T. solium infection in humans?

A
  • humans can also be intermediate hosts for T. solium, The cysticerci can form anywhere in the body
  • known as cysticercosis, neurocysticercosis
63
Q

Clinical signs of cystercercosis/neurocysticercosis

A
  • headache, confusion, seizures

- this is the leading cause of adult onset epilepsy

64
Q

what are the intermediate hosts of Non-taeniid tapeworms

A

arthropods

65
Q

What is the metacestode stage of non-taeniid tapeworms called?

A

cysticercoid

66
Q

What does a cysticercoid look like?

A

a small cyst with an invaginated single scolex, no fluid filled bladder

67
Q

What are the definitive and intermediate hosts of Dipylidium caninum?

A
  • definitive: canids and felids

- intermediate: fleas

68
Q

Dipylidium caninum lifecycle

A
  • gravid segments released containing egg packets
  • flea larvae ingest these egg packets, allowing cysticercoids to develop
  • infection of definitive host follows ingestion of flea
69
Q

What is the PPP of D. caninum

A

2 weeks

70
Q

How do you diagnose D. caninum?

A
  • tapeworm segments in perianal area
71
Q

why can’t you see D. caninum eggs in a fecal float

A

the egg packets aren’t usually seen unless the segment has been broken up

72
Q

What is the clinical importance of D. caninum infection?

A

infections are usually subclinical, may cause scooting

- can be zoonotic. Children are most likely to be infected, but this is very uncommon

73
Q

What is crucial to breaking the D. caninum cycle?

A

year-round flea control

74
Q

Anoplocephala perfoliata is the most common and important non taeniid tapeworm for which species?

A

horses

75
Q

Moniezia spp. infect which host?

A

ruminants

76
Q

What is the intermediate host of ruminant and equine tapeworms?

A

pasture mites

77
Q

When are the definitive hosts of equine and ruminant tapeworms infected?

A

when they inadvertently ingest mites while grazing

78
Q

What is the clinical importance of Anoplocephala perfoliata?

A
  • while usually asymptomatic, this common infection can occasionally cause inflammation and ulceration.
  • more severe cases, it can be associated with perforation, intussusception
79
Q

T/F: it is difficult to diagnose Anoplocephala

A

true

80
Q

T/F: horses are routinely treated at least once per year because Anoplocephala is hard to diagnose

A

true

81
Q

T/F: Anaplocephala attach at the anterior end of the host GI tract.

A

false; they attach at the ileocecal junction

82
Q

T/F: Anaplocephala is long, and horses are generally only infected with a few adults

A

false; they’re short and horses can be infected with many at once

83
Q

T/f: Moniezia is a very common infection in ruminants, and is also easy to detect in fecal samples

A

true

84
Q

What are the shapes of Moniezia spp. eggs in cattle and small ruminants?

A
  • square shaped in cattle

- more triangular in small ruminants

85
Q

Clinical significance of Moniezia infections?

A
  • while it appears dramatic, it does not appear to have any significant effect on production
86
Q

T/F: avian tapeworms can be pathogenic in large numbers

A

true

87
Q

where would you expect to find cyclophyllidean tapeworms in birds?

A

in the small intestine

88
Q

Which worm is associated with class Trematoda

A

flukes

89
Q

Two orders of flukes

A
  • Digenea (important flukes of domestic animals and humans)

- Monogenea (important external parasites of fish, reptiles, and invertebrates

90
Q

Physical morphology of Order Digenea

A
  • leaf-shaped
  • unsegmented
  • 1-2 suckers
91
Q

Where are Digenea eggs passed?

A

in feces

92
Q

How many intermediate hosts do Digenea flukes have?

  • what is always the first intermediate host?
A

usually two

snails (which species of snail depends on which species of fluke)

93
Q

Lifecycles of Trematode

A
  • adult produces eggs
  • egg hatches in water, ciliated larval stage hatches
  • larvae swims to specific snail host, though some use land snails that ingest the egg
94
Q

T/F: asexual development of Trematode occurs in the snail

A

true

95
Q

What is the Trematode stage that emerges out of snails called

A

Cercaria

96
Q

How do Cercaria reach their hosts?

A
  • in water, they usually swim to it

- on land, they get ingested by the next host

97
Q

What are larvae called when they are consumed by or attached to the second intermediate host?

A

metacercaria

98
Q

How does the metacercaria get into the definitive host

A

ingestion

99
Q

Where do the adults of Fasciola hepatica and Fascioloides magna live in their definitive hosts?

A
  • Fasciola hepatica: liver and bile ducts of ruminants, rabbits, people, dogs, etc.
  • Fascioloides magna: white-tailed deeer
100
Q

Where do cercaria of F. hepatica encyst and become metacercaria?

A

on vegetation or debris. and they they wait to be consumed by the definitive host

101
Q

After ingestion, where do larval flukes migrate?

A
  • larval flukes migrate through intestinal wall to liver
  • this migration in the liver may take several weeks
  • Then enters bile duct and matures
102
Q

Clinical importance of F. hepatica in cattle

A

can be a chronic disease, characterized by:

  • anemia, hypoproteinemia
  • weight loss, decreased milk production
  • immunity will gradually develop
103
Q

Why is clinical F. hepatica more severe in small ruminants than cattle?

A
  • acute damage from larval migration can occur

- Black Disease (Clostridium)

104
Q

What are the geographical US regions of clinical importance in regards to F. hepatica?

A
  • Gulf Coast States
  • Pacific northwest
  • Hawaii
105
Q

How is F. hepatica diagnosed?

A
  • patient history and clinical signs

- fecal exam, using the SEDIMENT procedure (not very sensitive)

106
Q

Control of F. hepatica

A

good management: drain, fence out wet areas to prevent spread of larval stages and snails

107
Q

What geographical regions is Fascioloides magna more important in?

A
  • Midwest and Northeast US
108
Q

T/F: F. If a sheep or goat is infected with a magna larvae, it will continue to move around until the host dies

A

true

109
Q

What is the 2nd intermediate host and definitive host of Nanophyetus salmincola

A
  • 2nd host: fish

- DH: dogs

110
Q

What is the importance of N. salmincola

A

it is a disease vector for a ricettsia organism that causes “salmon poisoning” in dogs