Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Oncology > Paraneoplasitc Syndromes > Flashcards

Paraneoplasitc Syndromes Flashcards

1
Q

Paraneoplastic syndroms alteration in

A

Structure / function occurring distant to the tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Causes of paraneoplastic syndrome

A

Production of small molecules released into circulation and immune cross reactivity between malignant and normal tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How do you treat PNS

A

Treat tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypercalcemia value

A

iCal > 1.6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Most common paraneoplastic syndrome

A

Hypercalcemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hypercalcemia of malignancy is less common in

A

Cats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tumor associated with hypercalcemia of malignancy in dogs

A

lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tumors associated with hypercalcemia of malignancy in feline

A

Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Malignancy panel can diagnose

A

Hyperparathyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Abscess of PTHrP does not mean

A

Pet is cancer free

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

2/3 dog with high calcium are diagnoses with

A

Cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Consider hospitalization when

A

Ionized calcium is greater than 1.8, Ca x Phos > 70, clinical signs - azotemia and dehydration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Rehydration does with hypercalcemia with

A

0.9 % NaCl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Rehydration does with hypercalcemia with

A

0.9 % NaCl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How do you treat hypercalcemia once rehydrated

A

Furosemide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

After using furosemide what can be used in treatment

A

Biphosphates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Biphosophonates

A

Inhibit osteoclasts - Zoledronate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Causes of feline hypercalcemia

A

SHIRT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Shirt

A

Spurious, hyperparathyroidism, idiopathic, renal disease, tumors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

c/s hypercalcemia

A

Vomiting, lethargy, anorexia, Melena

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Lab findings with hypercalcemia

A

Anemia, increased BUN, decreased Albumin

22
Q

What causes GI ulceration from hypercalcemia

A

Mast celll degranulation leads to excess histamine

23
Q

How do you treat GI ulceration from hypercalcemia

A

Treat tumor, omperazole, ,sucralfate

24
Q

Hyperviscocity syndrome

A

Increase blood components - increase blood viscosity

25
Q

HVS causes

A

End organ damage

26
Q

What organs are affected by HVS

A

Brain, arteries, retina, kidney, heart

27
Q

Multiple myeloma

A

Cancer of plasma cells that make excess Ig

28
Q

What are the TP and globulin in multiple myeloma

A

Increase TP and increase globulin

29
Q

Clinical signs of multiple myeloma

A

Lameness, epitaxy’s, PU/PD, neuro, cytopenias, increased calcium

30
Q

Need what for myeloma diagnosis

31
Q

M LOM

A

Monoclonal gammopathy, light chains, osteoblasts, marrow Plasmacytosis

32
Q

Monoclonal gammopathy

A

Increase globulins and spe

33
Q

Light chains significance in myeloma

A

Spill over into urine, not detected on dipstick

34
Q

Osteolysis significance in myeloma

A

Punched out lesions or osteopenia and rare in cats

35
Q

Marrow significance with myeloma

A

Marrow plasmacytosis - rare in cats

36
Q

Hyperestrogenism causes

A

Bone marrow hypoplasia, alopecia and feminization syndrome

37
Q

What can cause hyperestrogenism

A

Serotolli cell tumor and cryptorchism

38
Q

10% of dogs with malignant tumors have

39
Q

What is the most common tumor causing DIC

A

Hemangiosarcoma

40
Q

Myasthenia gravis

A

Antibodies to AChR block transmission at NM junction

41
Q

Myasthenia Gravis is associated with

42
Q

C/s of myasthenia gravis

A

Intermittent muscle weakness, exercise intolerance, regurgitation, megaesophagus, Dysphagia

43
Q

Thymoma is more common in

A

Older dogs and cats

44
Q

Thymoma

A

Cranial mediastinal mass

45
Q

Do Thymoma usually spread

46
Q

TX of Thymoma

A

Surgical removal, radiation, cholinestrase inhibitor

47
Q

Hypertrophic osteopathy

A

Overproduction of periosteum

48
Q

Hypertrophic osteopathy preferentially affect

A

Long bones

49
Q

How do you DX hypertrophic osteopathy

A

Radiographs, nodular, radiating 90 degree from long axis of affected bone

50
Q

Hypertrophic osteopathy cause neoplasia

A

Primary lung tumor or pulmonary metastasis

51
Q

How do you treat hypertrophic osteopathy

A

Remove underlying, multimodal pain control, euthansia

Oncology (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions