3 - Neoplasia

Question 1

Benign tumor

Answer 1

Tumor that does not invade surrounding tissue or metastasize

Question 2

Malignant tumor

Answer 2

Neoplasm that is locally invasive or metastatic

Question 3

Grade

Answer 3

Assessment of the clinical behavior of malignant neoplasms based on their microscopic appearance

Question 4

Stage

Answer 4

Indication of the exten of tumor growth and spread throughout the body

Question 5

What is used to determine treatment plan and prognosis

Answer 5

Stage

Question 6

Microscopic assessment of grading parameters may include

Answer 6

Degree of differentiation, number of mitosis, architectural features

Question 7

Clinical assessment of staging may include

Answer 7

Tumor size, degree of local invasion, lymph node involvement, presence of distance metastases

Question 8

Grading is performed by

Answer 8

Pathologist

Question 9

Staging is performed by

Answer 9

Clinician

Question 10

Which demonstrated extent of neoplasia within the patient

Answer 10

Staging

Question 11

All grading species are

Answer 11

Canine

Question 12

Most frequently diagnoses malignant cutaneous neoplasia in dog s

Answer 12

Canine mast cell tumor

Question 13

Subcutaneous canine mast cell tumor

Answer 13

If the entire neoplasia is below the level of the adnexal structure

Question 14

What is almost always in canine mast cell tumors

Answer 14

Eosinphils

Question 15

Canine mast cell tumor grading system

Answer 15

Low grade and high grade

Question 16

Grading of lymphoma in small animals is based on

Answer 16

Histologic tumor features in the lymph nodes

Question 17

Lymphoma what is the cornerstone of grading

Answer 17

Mitotoic activity

Question 18

Lymphoma grade is based on

Answer 18

Mitosis count

Question 19

Lymphoma size is based on

Answer 19

Nuclear size in comparison to RBC

Question 20

Small lymphoma is

Answer 20

Less 1.5 x size of RBC

Question 21

Intermediate lymphoma is

Answer 21

1.5 - 2 x a RBC

Question 22

Anaplastic neoplasm

Answer 22

Tumor in which cells do not resemble any normal cell type and for which teh tissue of origin cannot be determined

Question 23

Location matters especially in

Answer 23

Melanocytic neoplasma

Question 24

Why is my biopsy non diagnostic

Answer 24

Too small, crush artifact, cautery, poor fixation

Question 25

Antibody binding is detected by

Answer 25

Chromogen associated color change

Question 26

Immunohistochemistry may aid in identifying

Answer 26

Poorly differentiated neoplasma

Question 27

B cell marker

Answer 27

Pax5, CD79a, CD20

Question 28

Immunohistochemistry

Answer 28

Application of antibodies to tissue sections that bind to specific antigen

Question 29

PARR asses

Answer 29

Clonality

Question 30

PARR may be useful to differentiate neoplastic from

Answer 30

Inflammatory lymphocytes

Question 31

Flow cytometry can count

Answer 31

Cells and identify them by surface markers

Question 32

For a flow cytometry needs to be used on

Answer 32

Fresh tissues or live cells

Question 33

How do tumors metastasize pathways

Answer 33

Lymphatic vessel, blood, direct seeding

Question 34

Transmissible tumors

Answer 34

TVT, DFTD, BTN

Question 35

Lymphatic vessels pathway spread is often

Answer 35

Carcinomas

Question 36

Blood vessels spread to

Answer 36

Lung and liver