Paper3 Schizophrenia Flashcards
Positive symptoms
Additional experience
Negative symptoms
Loss of usual ability
Hallucinations
Sensory experience of things that aren’t there
Delusions
Irrational beliefs of grandiose or religion or paranoia
Speech disorganisation
Changing topic of conversation quickly
Catatonia
Unusual movement
Flat affect
Lack of emotional expression
Avolition
Lack of motivation
Polygenic
Two or more genes determine disorder
Aetiologically heterogenous
Number of different combinations of genes that lead to illness
RIPKE(2014)
108 genetic loci associated with schizophrenia
Suggests aetiologically heterogenous disorder
External reliability
Consistency of results from test when repeated
Inter rater reliability
Consistency of investigators observing study
Validity of schizophrenia
Extent to which it is a syndrome with specific characteristics or mixture of other disorders
Validity of diagnosis
Are we correctly diagnosing disorder