Pancreaticobiliary Diseases (Quiz 3) Flashcards

1
Q

the gallbladder is _____ during the fasting state

A
  • relaxed
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2
Q

the gallbladder is ______ during the postprandial state

A
  • contracted
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3
Q

what does chole mean

A
  • bile or gall
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4
Q

what does cholecysto mean

A
  • bile sac
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5
Q

what does choledocho mean

A
  • bile duct
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6
Q

what does cholangio mean

A
  • bile duct
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7
Q

what does cholestasis mean

A
  • stasis of bile in gallbladder
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8
Q

what does biliary colic mean

A
  • spasm of biliary tree causing pain
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9
Q

what does cholelithiasis mean

A
  • gallstones
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10
Q

what does choledocholithiasis mean

A
  • gallstones in bile duct
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11
Q

what does cholecystitis mean

A
  • inflammation of gall bladder
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12
Q

what does cholangitis mean

A
  • inflammation of bile ducts
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13
Q

what is the most common type of gallstone

A
  • cholesterol
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14
Q

where are cholesterol gallstones located

A
  • gallbladder
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15
Q

where are black gallstones located

A
  • gallbladder
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16
Q

what is the calcium and bilirubin content of black gallstones

A
  • high
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17
Q

where are brown gallstones located

A
  • bile ducts
18
Q

what is the pathogenesis of brown gallstones

A
  • infectious
19
Q

which sex is most predisposed to gallstones

A
  • females
20
Q

what presents with RUQ pain, fever, normal LFTs, but increased WBC count

A
  • cholecystitis
21
Q

what presents with acholic stool and dark urine

A
  • choledocholithiasis w/ obstruction
22
Q

what is Charcot’s triad

what is it associated with

A
  • fever
  • RUQ pain
  • jaundice
  • ascending cholangitis
23
Q

what is the function of the exocrine pancreas

functional unit

A
  • secretes digestive enzymes and proenzymes into a system of ducts
  • acinus
24
Q

what is an acute inflammatory disorder of the pancreas that is commonly associated with fever, nausea, abdominal pain, and elevated pancreatic enzymes in the blood

A
  • acute pancreatitis
25
Q

what is the final common pathway of acute pancreatitis

leads to

A
  • premature activation of digestive enzymes

- autodigestive necrosis of pancreatic tissues

26
Q

how does gallstone pancreatitis occur

A
  • gallstone passes into common bile duct and lodges in ampulla
  • trypsinogen activates to trypsin within the pancreas and causes tissue destruction
27
Q

how do we diagnose interstitial edematous acute pancreatitis

A
  • elevated amylase and/or lipase
  • check LFTs
  • ultrasound
28
Q

between amylase and lipase, which is more sensitive?

which is more specific

A
  • amylase is sensitive

- lipase is specific

29
Q

cholestatic pattern of elevated LFTs shows what

A
  • elevated bilirubin and/or alkaline phosphatase
30
Q

what is severe pancreatitis with extensive peripancreatic and pancreatic tissue destruction

due to

A
  • necrotizing acute pancreatitis

- systemic inflammatory response

31
Q

two signs pathognomonic for necrotizing acute pancreatitis

A
  • Cullen sign

- grey-turner sign

32
Q

complications of necrotizing acute pancreaitis

A
  • pseudocyst
  • duct rupture
  • fistula
33
Q

what are collections of fluid surrounded by inflamed fibrous tissue

A
  • pseudocyst
34
Q

what is a progressive fibroinflammatory disorder of the pancreas associated with a loss of pancreatic parenchyma and function

A
  • chronic pancreatitis
35
Q

diagnostic tests for chronic pancreatitis

A
  • low fecal elastase levels

- pancreatic calcification

36
Q

what’s a big difference grossly between acute and chronic pancreatitis

A
  • acute - enlarged pancreas

- chronic - shrunken pancreas

37
Q

complications of chronic pancreatitis

A
  • pseudocyst
  • splenic vein thrombosis
  • cancer
38
Q

strong association for pancreatic adenocarcinoma

A
  • tobacco
39
Q

why is pancreatic ductal adenocarcinoma so hard to resect

A
  • lot of structures close to the pancreas

- metastasis

40
Q

what is common in the adjacent tissue of ductal adenoarcinoma

A
  • chronic pancreatitis
41
Q

jaundice is common with tumors of which part of the pancreas

A
  • head