LFT Recap (Quiz 3) Flashcards

1
Q

where is ALT located in the hepatocyte

A
  • cytoplasm
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2
Q

where is AST located in the hepatocyte

A
  • mitochondria
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3
Q

what medication can cause pre-hepatic jaundice

A
  • rifampin
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4
Q

what happens in Dubin-Johnson syndrome

A
  • bilirubin can’t be exported from hepatocyte to bile duct
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5
Q

what happens in Rotor syndrome

A
  • bilirubin can’t stay stored in hepatocyte
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6
Q

with which disease do you see a black liver

A
  • Dubin-Johnson
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7
Q

AST/ALT ratio for alcoholic liver disease

A

2-3:1

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