Pancreatic Hormones

Question 0

Insulin

Answer 0

Storage and anabolic hormone

Proper glucose use

Question 1

Glucagon glucagen

Answer 1

Severe hypoglycemia
Diagnostic aid
Beta blocker poisoning
Ae- transient and mild

Question 2

Ultra short acting

Answer 2

Preprandial

Duration not prolonged with hIgher dose

Question 3

Short acting insulin

Answer 3

Given iv or infusion pumps
Duration increases proportional to dose
Hypoglycemic emergencies
For diabetic ketoacidosis

Question 4

Intermediate acting insulin

Answer 4

Rapid absorption plus sustained long duration

Question 5

Lipodystrophy

Answer 5

Atrophy of subcutaneous fat

Hypertrophy of subcutaneous fatty issue

Question 6

Sensitizers and secretagogues

Answer 6

Sensitizers- inc insulin sensitivity

Secretagogues- inc insulin secretion

Question 7

Biguanides

Answer 7

Formins
Phenformin discontinued due to lactic acidosis
Moa- direct stimulation of glycolysis
Anti-hyperglycemic agent

Question 8

Peroxisome proliferator activated receptor

Answer 8

Alpha- for hyperlipidemia, target of fibrate drugs
Beta/delta- changes the body’s fuel preference from glucose to lipids
Gamma- affected by thiazolidinediones

Question 9

Dual ppar modulators

Answer 9

Glitazars

Fourth class

Question 10

Thiazolidinediones

Answer 10

Glitazones
Inc target tissue sensitivity
Decreased insulin resistance
May cause hepatotoxicity
Oral hypoglycemic