Pancreas lecture Flashcards
Function of the pancreas
Exocrine (digestive) functions
Endocrine functions
What does the pancreas secrete
insulin
glucagon
amylin
somatostatin
pancreatic polypeptide
Islet of langerhans
Alpha- glucagon
beta- insulin
delta- somatostatin
pancreatic polypeptide-
Acini
glands that secrete digestive enzymes into the duodenum
What is insulin stimulated by
high blood sugar
amino acids
beta keto acids
acetylcholine, intestinal hormones
beta agonists
what inhibits insulin
low blood glucos
glucagon
cortisol
catecholamines
GH
somatostatin
insulin half life
7 minutes
insulinase degrades unused insulin in liver, some degraded by kidney and muscles
What does insulin do
Causes carbs to be stored as glycogen in muscle and liver, if not they are stored as fat
Promotes uptake of amino acids and conversion to protein
increases glycogenesis, decreases glycogenolysis
With insulin, what does the cell membrane increase intake of?
amino acids, phosphate, potassium
Insulin facilitates entry of glucose into cells except in the ____
brain
kidney tubules
RBCs