Pancreas-Exam 2 Flashcards

1
Q

What is the left limb of the pancreas supplied by? (blood vessel)

A

Splenic a.

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2
Q

What is the body/right limb of the pancreas supplied by?

A

Caudal pancreaticoduodenal a. (branch of cranial mesenteric a.)

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3
Q

What duct drains the R lobe and enters the duodenum at the major duodenal papilla w/ bile duct?

A

Pancreatic duct- drains R lobe

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4
Q

What is the difference in the duct system in cats vs. dogs?

A

Cats don’t have an accessory duct

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5
Q

What drains in to the minor DP in dogs?

A

Accessory pancreatic duct- drains L lobe

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6
Q

What do the following pancreatic cells produce?

A, B, D, F/P

A

A: glucagon
B: insulin
D: somatostatin
F/P: pancreatic polypeptide

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7
Q

T/F: Pancreatitis is a sx disease?

A

FALSE- common but not sx

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8
Q

What biopsy method is used for the pancreas?

A

Guillotine technique

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9
Q

What is indicated for a pancreatic tumor removal?

A

Partial pancreatectomy

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10
Q

What are the best tools for dissecting lobules?

A

Hemoclips or bipolar cautery

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11
Q

If the remaining ducts are patent in the pancreas-what percentage can be removed?

A

80%

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12
Q

What is the most common complication associated with partial pancreatectomy?

A

Pancreatitis

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13
Q

What happens if pancreatic drainage is completely obstructed?

A

Exocrine pancreatic insufficiency

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14
Q

What is the tx of exocrine pancreatic insufficiency?

A

Pancreatic enzyme supplementation & low fat/highly digestible food

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15
Q

What occurs when over 80-90% of the pancreas is removed?

A

Endocrine pancreatic insufficiency

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16
Q

What is the tx for endocrine pancreatic insufficiency?

A

Insulin

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17
Q

What can occur if you accidentally ligate vessels that are around the R lobe of the pancreas?

A

Devitalization of duodenum

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18
Q

What is the instrument of choice for pancreatic sx?

A

Ligasure

19
Q

Why are pancreatic pseudocysts not true cysts?

A

Lack epithelial wall

20
Q

T/F: Pancreatic pseudocysts are often incidental findings

A

TRE

21
Q

What is the test of choice for pancreatic pseudocyst?

A

US- most sensitive

22
Q

T/F: You cannot differentiate pseudocyst from abscess on US

A

TRUE

23
Q

What is the first line tx for pancreatic pseudocyst?

A

Percutaneous aspiration- especially if aclinical

24
Q

What is the tx of choice for cure of pseudocysts?

A

Omentilization

25
Q

What is typically secondary to acute bouts of pancreatitis?

A

Pancreatic abscess

26
Q

T/F: Most pancreatic abscesses are sterile

A

TRUE

27
Q

What ab data supports pancreatic abscesses?

A

Hyperbilirubinemia/elevated LEZ due to EHBO- inflammation of pancreas causing duodenal papilla of CBD to swell shut

28
Q

What is the best method of sx management for pancreatic abscesses?

A

Omentalization

29
Q

What is a rare but highly malignant tumor in dogs that arises from APUD cells

A

Gastrinoma

APUD: amine precursor uptake decarboxylase cells

30
Q

What is the zollinger-ellison syndrome?

A

Syndrome of gastric acid, hypersecretion, gastrointestinal ulceration & non-B cell pancreatic tumors

31
Q

What is a diagnostic factor for gastrinoma?

A

High serum gastrin levles

32
Q

What is a malignant and locally invasive tumor in the pancreas?

A

Exocrine pancreatic adenocarcinoma

33
Q

What is the prognosis of a patient with exocrine pancreatic adenocarcinoma?

A

Poor

34
Q

What is insulinoma?

A

B-cells of islets of Langerhans–> secrete insulin despite hypoglycemia

35
Q

What % of insulinoma is malignant?

A

90%

36
Q

What are the components of the whipples triad?

A

CS associated w/ hypoglycemia
Fasting blood glucose concentration of 40 mg/dL or ower
Relief of neurological signs w/ feeding or glucose administration

37
Q

What is a def dx for insulinoma?

A

Fasting insulin glucose ratio

Insulin HIGH despide hypoglycemia

38
Q

What are the normal fasting serum levels?

A

5-26 mg/dL

Affected animals > 70 mg/dL

39
Q

What are some medical management methods for insulinoma

A

Small frquent meals (high protein, complex carbs)
Glucocorticoid therapy
Oral hyperglycemic agents- DIazoxide

40
Q

What is the gold standard sx tx for insulinoma?

A

Partial pancreatectomy

41
Q

What are the MST for the following insulinoma situations:
No sx
Sx
Sx + medical therapy

A

No sx: 196 days
Sx: 785 days
Sx + medical management: 1316 days

42
Q

What is the main medication used in patients with insulinoma when combined with sx?

A

Pred

43
Q

What is the difference of MST for the following stages
I
II
III

A

I: 785 days
II: 547 days
III: 217 days