Pancreas Flashcards
Three stages of pancreatitis
1 intrapancreatic enzyme activation and acinar cell injury
2 chemoattraction of neutrophils
3 release of proteolytic enzymes onto distant organs
SIRS criteria
Systemic Inflammatory Response Syndrome,
Temp 38
Hr > 90bpm
Tachypnea >20 breath per min
WBC 12x10^9/L
Two most common causes of acute pancreatitis
Gallstones, alcohol
Infectious causes of acute pancreatitis
CMV, mumps, rubella, coxB
Classic presentation of AC
Pain in epigastrum and radiates to back
Nausea and vomiting
Fever
Hypotension or shock
What are Turner sign and Cullen sign?
Blushing color around flanks (turner) and umbilicus (cullen)
Signs present in severe but not mild acute pancreatitis
Rebound tenderness
Bowl sounds are absent
Ascites or shifting dullness
Laboratory marker of choice for acute pancreatitis
Serum Amylase (3x or more original value)
Urinary Amylase (lasts longer than serum amylase)
Serum Lipase (most accurate b/c solely pancreatic origin)
Amylase Creatinine Clearance Ratio (ACR)
normal and AP values
normal: 3.8-5.3%
AP: 5-6%
What a CT scan can show about AP
***Pancreatic necrosis (lack of enhancement after contrast medium bolus injection)
inflammation, thrombosis, fluid collection
Cause of pancreatic abscess?
Gas-forming microorganisms
Drug to relax sphincter of oddi
Magnesium sulfate