Pancreas Flashcards

0
Q

Three stages of pancreatitis

A

1 intrapancreatic enzyme activation and acinar cell injury

2 chemoattraction of neutrophils

3 release of proteolytic enzymes onto distant organs

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1
Q

SIRS criteria

A

Systemic Inflammatory Response Syndrome,

Temp 38
Hr > 90bpm
Tachypnea >20 breath per min
WBC 12x10^9/L

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2
Q

Two most common causes of acute pancreatitis

A

Gallstones, alcohol

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3
Q

Infectious causes of acute pancreatitis

A

CMV, mumps, rubella, coxB

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4
Q

Classic presentation of AC

A

Pain in epigastrum and radiates to back
Nausea and vomiting
Fever
Hypotension or shock

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5
Q

What are Turner sign and Cullen sign?

A

Blushing color around flanks (turner) and umbilicus (cullen)

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6
Q

Signs present in severe but not mild acute pancreatitis

A

Rebound tenderness
Bowl sounds are absent
Ascites or shifting dullness

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7
Q

Laboratory marker of choice for acute pancreatitis

A

Serum Amylase (3x or more original value)

Urinary Amylase (lasts longer than serum amylase)

Serum Lipase (most accurate b/c solely pancreatic origin)

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8
Q

Amylase Creatinine Clearance Ratio (ACR)

normal and AP values

A

normal: 3.8-5.3%
AP: 5-6%

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9
Q

What a CT scan can show about AP

A

***Pancreatic necrosis (lack of enhancement after contrast medium bolus injection)

inflammation, thrombosis, fluid collection

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10
Q

Cause of pancreatic abscess?

A

Gas-forming microorganisms

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11
Q

Drug to relax sphincter of oddi

A

Magnesium sulfate

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