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Medicine > Palliative care > Flashcards

Palliative care Flashcards

1
Q

What is the MOA of paracetamol?

A

Weak COX inhibitor

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2
Q

What is the 1st line NSAID in palliative care?

A

Celecoxib

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3
Q

What is the MOA of opioids?

A

Mu agonist

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4
Q

How does metoclopramide work and what is it used for?

A

Quickens gastricic emptying

Useful for nausea and is often used in conjunction with dexamethasone for partial BO (unless there is colic)

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5
Q

What might Domperidone interact with and what effect might this have?

A

Domperidone + ondansetron => QT prolongation

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6
Q

What is the 1st line anti-emetic in palliative care?

A

Cyclizine

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7
Q

What are hyoscine and glycopronium used as?

A

anti-secretory

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8
Q

Which medications should be used to treat intestinal secretions?

A

Hyoscine,
Octreotide

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9
Q

Name 3 weak opioids

A

Codeine
Dihydrocodeine
Tramadol

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10
Q

Name 5 strong opioids

A

Morphine
Oxycodone
Methadone
Buprenorphine
Fentanyl

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11
Q

How do you convert an oral morphine dose to an SC dose?

A

divide by 2

However for oral morphine to SC diamorphine, divide the 24 hour oral morphine dose by 3

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12
Q

what dose of SC Alfentanyl (hourly) and Transdermal Fentanyl is equivalent to 30mg 2hr oral moprhine?

A

1mg SC Alfentanyl (hourly)

12mg transdermal Fentanyl

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13
Q

How do you calculate the transdermal fentanil dose from the 24 hour oral morphine dose?

A

multiple the 24 hour oral morphine dose by 2/5

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14
Q

If pain is not controlled, by how much should you increase your dose of analgesia?

A

30-50%

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15
Q

Which opioid should you give in renal impairment and hepatic impairment?

A

Hepatic impairment -> morphine

Renal Impairment
Mild / moderate - oxycodone
severe - buprenorphine, alfentanil, fentanyl

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16
Q

Name 3 SEs of Omeprazole

A

Hyponatraemia
Osteoporosis
^risk c.Diff

17
Q

How would you manage spasmodic back pain in palliative care patients?

A

Diazepam

18
Q

What might you use to manage a painful mouth at the end of life?

A

Benzydamine hydrochloride

19
Q

What is the 1st line management of agitation in palliative care?

A

Haloperidol

Medicine (22 decks)

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