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Medicine > Oncology > Flashcards

Oncology Flashcards

1
Q

What is cryoprecipitate acetate and why is it used?

A

Anti-androgen

You give this to avoid the temporary worsening of symptoms when using goserelin for prostate cancer

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2
Q

What is the MOA of Goserelin?

A

GnRH agonist

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3
Q

What are epirubicin / doxorubicin used for?

A

Breast cancer

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4
Q

What is anastrozole and what is it used for?

A

aromatase inhibitor used as homrone therapy for ER+ breast cancer

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5
Q

What is Tamoxifen and what is it used for?

A

It’s herceptin, a mAb for HER2R

Breast cancer

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6
Q

What is Cetuximab and what is it used for?

A

EGFR mAb for non-small cell lung cancer and head and neck SCC

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7
Q

How would you manage Tumour Lysis Syndrome?

A

IV Fluids
Allopruniol / Rasburicase

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8
Q

What are the medication options for breast cancer?

A

Chemo - anthacyclines (epirubicin, doxorubicin)

Oestrogen sensitive - aromatase inhibitors

HER2+ - temoxifen

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9
Q

What type of imaging should you use in colon cancer?

Which is not appropriate?

A

CT colonography

Not barium enema

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10
Q

How would you differentiate seminoma from non-seminoma testicular cancers?

A

Both have ^bHCG

Non-seminoma also have ^AFP

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11
Q

PWhich chemotherapy agent is associated with hypomagnesaemia?

A

Cisplatin

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12
Q

What are the features of MEN1 syndrome?

A

Cancers of:
Pituitary
Parathyroid
Pancreas

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13
Q

What are the features of MEN2A syndrome?

A

Cancers of:
Medullary thyroid cancer
Phaemochromocytoma
Parathyroid adenoma

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14
Q

What are the features of MEN2B syndrome?

A

MEN 2A +…

Mucosal neuroma
GI
Craniosynostosis

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15
Q

What is the imediate management for SVCO?

A

Dexamethasone

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16
Q

Can you give another name for pip-tazo?

A

Tazocin

17
Q

What is the histological sign of papillary thyroid cancer?

A

Orphan Annie cells

18
Q

Which lung cancer type is most closely associated with smoking?

A

squamous cell lung cancer

19
Q

What is 1st and 2nd line for treating pathological fractures in bone metastases?

A

1 - bisphosphonates (alendronic acid)

2 - Denosumab

20
Q

What are the 2 main features of Kartagener’s syndrome?

A

1) Situs Inversus
2) Immotile cilia syndrome

21
Q

Which cancers are associated with raised platelets?

A

LEGO-C

Ling
Endometrial
Gastric
Oesophageal
Colorectal

Medicine (22 decks)

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