Dermatology Flashcards
What is the first line agent for acute urticaria?
Loratidine (non-sedating antihistamine)
Name 3 non-sedating antihistamines
Loratidine
Fexofenadine
Cetirizine
Which 2 agents are used in the management of malignant melanoma?
Nivolumab
Ipilimumab
What is the MOA of Nivolumab?
anti-PD-1 mAb
What is the MOA of Ipilimumab?
anti-CTLA-4 mAb
What is Imiquimod used to treat?
Genital warts
BCC
Molluscum Contagiosum
What is 5-fluorouracil used for?
Genital warts
Bowen’s disease (SCC)
Actinic keratoses
Name 4 steroids used to treat eczema in order of increasing potency
Hydrocortisone, Eumovate, Betnovate, Dermovate
What is Brimonidine used for?
Reduces flushing in Acne Rosacea
What is Ivermectin used for?
Scabies
Moderate/severe Acne Rosacea
What 2 agents are used in the management of non-bullous impetigo?
1st line - hydroge peroxide
2nd line - fusidic acid
If widespread then consider oral flucloxacillin
What two agents are used to treat lice?
Malathion
Dimeticone
How would you manage TEN?
Stop precipitating factor
IV Ig
Co-Amoxiclav
How is eczema herpeticum managed?
aciclovir
How would you manage bullous pemphigoid?
Oral corticosteroids
How would you manage dermatitis herpeticum?
gluten-free diet
Dapsone
What risk is there with Dapsone?
May cause methaemoglobinaemia
How would you manage acute flares of hydradenitis suppurativa?
Steroids
oral Abx (lymecycline or clindamycin and rifampicin)
How is lichen planus managed?
potent topical steroids
Oral benzydamine mouthwash
How would you manage lichen sclerosus?
Topical steroids and emolients
How would you manage periorofacial dermatitis?
DO NOT OFFER STEROIDS (may worsen symptoms)
Offer topical / oral Abx
How would you manage pemphigus vulgaris?
Steroids
How would you manage psoriasis?
Calcipotriol + daily corticosteroid
may be combined in Dovobet or Enstilar
Why is a vitamin D analogue given with corticosteroids?
It counters epidermal dysregulation, inhibiting epidermal hyperprolieration and inducing keratinocyte differentiation
How long of a break should you give psoriasis patients on topical corticosteroids
4 weeks
How would you manage pyoderma gangrenosum?
Oral steroids
How would you manage infantile seborrhoeic dermatitis?
baby oil / veg oil / olive oil
if not then white petroleum jelly
if not then topical anti-fungal for 4 weeks (clotrimaole, miconazole)
How would you manage hirsutism?
COCP
Don’t use Co-cyprindiol in the long term because of VTE risk
Facial? -> topical eflornithine (contraindicated in pregnancy and breast-feeding)
Name 3 drugs causes hypertrichosis
minoxidil
ciclosporin
diazoxide
What is the first line agent for chickenpox?
Aciclovir
How might you treat itching symptoms in chickenpox?
Calamine lotion
Chlorphenamine
How would you manage Erythasma?
Topical miconazole or antibacterial
If extensive then oral erythromycin
How do you treat fungal nail infections?
Asymptomatic -> no treatment
Limited - topical amorolfine
More + dermatophyte - oral terbinafine
More + candida - oral itraconazole
How is headlice managed?
Dimeticone lotion, leave on for 8 hours
repeat 7 days later to kill any lice which have hatched since treatment
How is Mycosis fungoides managed?
Psoralen and UV A (PUVA)