Pain Physio (EB) Flashcards

1
Q

Why do people withhold analgesia

A

difficulties in recognizing pain. Lacking of knowledge in the appropriate use of analgesics. Fear of drug side effects

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2
Q

Why is it important to monitor the response to pain tx?

A

lots of consequences of pain

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3
Q

What 2 combinations of things is pain?

A

nociception and perception

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4
Q

What are the classic categorizations of pain (5)

A

disease Anatomy. General location Duration Intensity

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5
Q

What is physiologic/nociceptive pain? (3)

A

early-warning physiological protective system Touching things too hot, cold, sharp

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6
Q

What type of pain is essential for bodily integrity?

A

physiologic/nociceptive pain

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7
Q

What are the 2 types of pathological/clinical pain?

A

inflammatory Neuropathic

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8
Q

What type of pain is adaptive but still needs to be reduced?

A

inflammatory pain

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9
Q

What type pain must be treated?

A

neuropathic pain

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10
Q

What is the purpose of inflammatory pain?

A

assist in healing by discouraging physical contact or movement

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11
Q

What pain is not protective at all, just maladaptive?

A

neuropathic pain

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12
Q

What does neuropathic pain result from?

A

abnormal functioning of the NS

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13
Q

What fibers participate in nociception?

A

A-delta C A-beta

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14
Q

Pathway of nociception

A

transduction Transmission Modulation Projection Perception

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15
Q

What is the transduction of pain?

A

detection of innocuous and noxious information

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16
Q

What nerve fibers are responsible for “first pain” aka the pricking and sharp pain?

A

A-delta fibers

17
Q

What type of receptors are Adelta fiber nociceptors composed of?

A

75% of low-threshhold 25% of high-threshold

18
Q

What nociceptive fibers have a higher discharge rate?

19
Q

What nociceptive fibers have a high threshold?

20
Q

What nociceptive fiber has a second/slow pain?

21
Q

What fibers have to be activated for the perception of acute pain?

A

both the Adelta and C nociceptors

22
Q

What are the silent or sleeping nociceptors?

A

A delta and C fiber

23
Q

What activates the silent/sleeping nociceptiors?

A

inflammation NOT activated by tissue damaging events

24
Q

What stimulation are the silent/sleeping nociceptors very sensitive to?

A

mechanical

25
What fibers pick up a low intensity pain stimulus? What is their threshold?
A beta fibers Low threshold
26
What fibers pick up a high intensity pain stimulus? What is their threshold?
A delta and C fibers High threshold
27
What is it when A beta fibers are more easily excitable?
allodynia
28
What is it when A delta and C fibers are more easily excitable?
hyperalgesia
29
What does peripheral sensitization result in?
hyperalgesia at the site of injury (primary hyperalgesia)
30
What causes peripheral sensitization
inflammatory/sensitizing soup
31
What is responsible for pain memory?
central sensitization
32
What does central sensitization result in?
primary and secondary hyperalgesia and allodynia
33
What is wind-up
temporal summation of sensory inputs in the spinal cord
34
What drugs inhibit transduction of pain (4)
opioids Local anesthesia A2 agonists NSAIDs
35
What drugs inhibit transmission of pain (1)
local anesthesia
36
What drugs inhibit the perception of pain (5)
inhalants Sedatives Injectables Anesthesics NSAIDs
37
What drugs inhibit the projection of pain (6)
inhalant anesthetics Injectable anesthetics Local anesthetics Opioids A2 agonists ketamine