Pain and thermatosensation outcomes Flashcards
Where are the cell bodies of nociceptors located?
Dorsal root ganglia and trigeminal ganglia
These fibres mediate first/fast pain
Which stimuli do they respond to?
A-delta fibres
(myelinated)
-mechanical/thermal stimuli
These fibres mediate second/slow pain
C fibres
-respond to ALL stimuli
Most nociceptive C- and Aδ-fibres termination superficially in which laminae?
Laminae I and II
How do visceral afferents reach the dorsal horn?
Follow sympathetic pathways
The 2 nociceptive tracts
Spinothalamic Tracts
Spinoreticular tracts
What type of pain fibres in the spinothalamic tracts?
Fast fibre Aδ
WDR fibres
Where do Aδ neurones from lamina I terminate?
In the posterior nucleus of the thalamus
Where do WDR neurones from lamina V terminate?
In the ventroposterior and posterior nucleus of the thalamus
What type of pain fibres in the spinoreticular tract?
Slow C-type fibres
Where does the spinoreticular tract connect in the brain?
Connects to reticular nuclei in the brainstem
e.g. PAG and parabrachial nucleus (PB)
This tract is involved in autonomic response to pain, arousal, emotional responses, fear of pain
Spinoreticular tract
What is the spinoreticular tract involved in?
Involved in autonomic responses to pain, arousal, emotional responses, fear of pain
