Paediatrics 2 Flashcards
Name some specific types of epilepsy that can be diagnosed in a child:
Childhood onset Absent seizures
~ 6 years old
- Sodium Valproate
- Ethosuximide
Lennox- Gastuat syndrome
- multiple seizure types, usually atonic
- cognitive impairment
- Slow spike wave on EEG
Juvenile myoclonic epilepsy
- muscle twitches/ contractions/ jumps
West’s syndrome/ Infantile spasms:
~4-6 months
- Extension of trunk and extension of arms
- usually underlying neurological condition
- poor prognosis
- predinislone is 1st line
Dravet syndrome
- severe myoclonic epilepsy
- resistant to drugs
What are the different types of cerebral palsy seen?
Spastic hypertonia
- motor cortex
Dyskinetic (basal ganglia)
- Athenoid (hyper movement, grimace, drooling)
- Dystonic
Ataxic
- cerebellum
What are some gait changes seen with cerebral palsy?
Circumductive gait
- seen with spastic hemiplegia
Scissoring
- spastic diplegia
Ataxic gait
What are some causes of cerebral palsy?
Antenatal:
- Maternal infection (rubella, toxoplasmosis)
- intrauterine injury
- maternal disease (hypothyroidism)
Perinatal:
- birth asphyxia
- pre-term
Post-natal:
- meningitis
- severe neonatal jaundice
- heady injury
What prostaglandin drug can be given to maintain the ductus arterioles?
Alprostadil
How is vesicoureteral reflux diagnosed and how is scarring assessed?
Micturating Cystourethrogram
- diagnosis
DMSA Scan
- for evidence of scaring
If a neonate goes into cardio-respiratory arrest and on auscultation you can hear tingling in the chest, what is the most likely diagnosis?
Diaphragmatic hernia
- leading to bowel within the thoracic cavity which affects lung maturity
Intubation is needed as the baby can fail quickly after birth
Causes pulmonary aplasia
What is your emergency treatment of croup?
High flow oxygen
Nebulised adrenaline
IV dexamethasone
*used for severe croup
What are some features of cystic fibrosis in the new born and later life?
Meconium ileus
Recurrent chest infections
Malabsorption
Nasal polyps
Later life:
- short stature
- delayed puberty onset
- male infertility
What are some features in children with cystic fibrosis (usually in those who were missed at birth)
Short stature
Reduced growth (drop in centiles)
Diabetes
Nasal polyps
What are the serious complications of measles?
Acute otitis media
Pneumonia
Encephalitis
- Subacute sclerosing panencephalitis
- appears some 5-10 years after infection due to reactivation and inappropriate immune response
- behaviour changes / personality changes
- memory changes
- Seizures
What investigations would be warranted into suspected biliary atresia?
Bilirubin
- conjugated
- unconjugated
LFTs
Sweat tests (check for cystic fibrosis)
Alpha -1 antitrypsin
Biopsy**
Ultrasound**
HIDA scan**
What testing is done at birth to assess for hearing loss, and what is the follow on test if abnormal?
Otoacoustic emission test
- small click generated which then creates an echo if the cochlear is normal
Auditory brainstem response
- done next if Otoacoustic emission test is abnormal
What is the formula for blood resuscitation in paediatrics?
Change in Hb (g) x Weight (kg) x 4
How is pyloric stenosis diagnosed and what will be seen? and what is the mangement?
Diagnosed via ultrasound
- thickened pyloric muscle
Correct Electrolyte imbalance
NG tube
Ramstedt pyloromyotomy
List some causes of bilious vomiting in a child:
Intestinal atresia Necrotizing enterocolitis Hirschsprung disease Intussusception Malrotation volvulus Meconium plug
What are the signs and symptoms of NEC and how is it investigated and treated?
Stable preterm who goes off feeding Abdominal distention Bloody stools Bilious vomit/ aspirates Pyrexia Haemodynamically unstable
Investigations:
- FBC **platelets reflect severity
- Cultures
- CRP
- ABG
- Culture stool
- Abdominal x-ray
- left lateral decubitus
Management:
- Stop feeds and insert TPN
- IV fluids
- Antibiotics IV broad spectrum
- NG tube - for aspirates
Surgical:
needed for stage III onwards
- bowel resection
- stoma formation
How does malrotation of the gut present and what is the diagnostic procedure?
Due to failure of intestinal rotation typically affected the duodenal-jejunal flexure which comes to lie on the right instead of the left of the midline.
Presentation:
- Bilious vomiting
- abdominal distention
- blood per rectum (late sign due to gut ischemia)
- Metabolic acidosis
Diagnosed:
- G.I contrast study
Treatment:
- IV fluids
- NG drainage
- IV broad spectrum antibiotics
- Emergancy laparotomy *surgical Emergancy
- if necrotic gut it removed and stoma
- if entire midgut is affected palliative care
What condition is intestinal atresia highly associatted with and what sign is seen on x-ray?
Down’s syndrome
Double bubble
What condition is a meconium plug associated with and how is it diagnosed and treated?
Cystic fibrosis
- 5-10& will have CF
Features:
- obstruction
- bilious vomit
Diagnosed:
- Gastrografin
Treatment:
- Bowel rest
- IV fluids
- NG tube decompression
- Antibiotics
- Gastrografin - breaks up material
if medical failure then:
- lapartomy +/- ileostomy
When approaching a Surgical abdomen what investigations should be done in what order?
History Examination Urine Beta hCG Blood tests Repeat examination Ultrasound
In a female child patient presenting with abdominal pain what must one make sure to ask:
Have they started menarche
What are the signs and symptoms of intussusception:
*most common place is the ileocaecal valve, usually due to enlarged Peyer Patches following viral infection (in older children there tends to be a history of HSP or lymphoma)
Abdominal pain
Pale and unwell
Redcurrent jelly stools
Floppy and hemodynamically unstable
Classic triad is:
- abdominal pain
- Bilious vomit
- redcurrent jelly stools