General Medicine and Surgery Flashcards
What is CEA used for?
Measuring response to surgery
What bloods should be done in the setting of colon cancer?
FBC
- anaemia
LFTS
- metastasis
What is the clinical findings on the tibia in people with Grave’s disease?
Pre-tibial myxoedema
What antibiotics can be used in MRSA who is penicillin allergic?
Linezolid
Clindamycin
Vancomycin
Doxycycline can be be given PO
When do you give tetanus vaccine/ immunoglobulins for a wound?
Nothing if they are up to date with their vaccines and they were delivered within 10 years.
Puncturing wound and >10 years since vaccines:
- tetanus vaccine
+/-
- immunoglobulin (if a large wound and large risk)
*same as above for unknown vaccination history
Do you treat asymptomatic bacteriuria in catheter patients?
no.
Which type of pneumonia is associated with guillain barre syndrome?
Mycoplasma
What are the core indications for dialysis:
Hyperuricemia
- encephalopathy
- pericarditis
Refractory metabolic Acidosis
Refractory hyperkalaemia
Diuretic resistant pulmonary oedema
Dialyzable toxins
- lithium
- salicylates
- alcohol metabolites (glycols)
How is Hydronephrosis managed in the acute setting?
Nephrostomy if upper tract obstruction
Suprapubic catheter is lower tract
What is the hormone that is released from the hypothalamus which stimulates the anterior pituitary to release TSH?
TRH
What are some side effects of sub-total thyroidectomy and radioactive iodine:
Radioactive iodine
- initial worsening of symptoms to begin with
Thyroidectomy
- bleeding, recurrent laryngeal nerve damage
- life long requirement of thyroxine
Colicky pain vs peritonitis:
Colicky:
- blocked visera
- Waves of pain
- move about a lot, can’t stay stll
Peritonitis:
- irratants/ infection to the parietal peritoneum
- constant pain
- rigid abdomen
- don’t want to move, stay very still
List some irratants to the peritoneum:
Blood Gastric juices Bile Pancreatic juice Urine
What are some signs of a DVT? What investigations should be conducted and what is the treatment?
Pain in the leg
Swelling
Pyrexia
Prominent leg veins
Well DVT
*need a score of >1 to trigger further investigation
which is an ultrasound
Treatment:
1st line: DOAC - apixaban
*note dabigatran requires LMWH
warfarin may be added for 3 months
What other things may raise the D-dimer?
Recent surgery
Infection
Liver disease
Pregnancy
In recurrent P.E which are known to be due to recurrent DVTs, what device can they have fitted to prevent this?
IVC filter
What is your management of a P.E?
Wells Score:
<4 = D- dimer
>4 = CTPA or V/Q scan
*if CTPA negative then do leg US
Management:
- Apixaban or Rivaroxaban (DOACs)
or
- LMWH
Continue DOACS for at least 3 months
LMWH switch to warfarin following 5 days for 3 months
In suspected pancreatitis what two tests must be done prior to a patient leaving the ED? and what is your general management?
Serum amylase
Erect chest x-ray (must rule out a perf)
IV fluids IV anti-emetics ABG - for oxygen support NG tube Catheter
*early feeding is recommended as it can help reduce the severity associated with pancreatitis
What type of surgery is conducted for primary parathyroid adenoma?
Minimally invasive - total parathyroidectomy
Which diabetic medication is delivered via subcutaneous injection (apart from insulin)?
GLP-1 Analogues
How often should diabetics monitored their blood glucose, presuming they are well?
4 times daily
- before each meal and before bed
Why is secondary hyperparathyroidism why is alendronic acid used even if the calcium is normal?
Reduced phosphate clearance results in increased PTH released in order to create more Ca2+ to bind to the phosphate.
What are some of the risk factors for gastric ulcers and duodenal ulcers:
Both:
- NSAIDs
- H.Pylori
Gastric:
- delayed emptying
- Smoking (induces reflux from duodenum)
Duodenum:
- Gastric hyperacitity
- smoking
- stress
*note that when a duodenal ulcer perforates it goes into the peritoneal cavity
when a gastric perforates it goes into the lesser sac
Coeliac disease: If the results are negative but coeliac is still suspected what should you do?
Test for IgA deficiency
- if deficient then request:
IgG for TTG and EMA
and/ or
Anti - deaminated gliadin peptide antibodies