P1 PATHOLOGY Flashcards
Osteomyelitis , infections of bones & joints
inflammation of bone & bone marrow caused by pyogenic bacterial infection is know as
pyogenic osteomyelitis
first site of infection in osteomyelitis
metaphysis of long bone
any bone
Vertebral column
this is a presentation of
chronic pyogenic osteomyelitis
Identify what is 3 pointed by arrow
main cloaca
Identify what is 2 pointed by arrow
involcrum
Identify what is 1 pointed by arrow
sequestrum
Identify what is 6 pointed by arrow
seen in case of chronic osteomyelitis
mixed inflammatory exudate
Identify what is 5 pointed by arrow
seen in case of chronic osteomyelitis
bone trabeculae
when pus penetrates Haversian system of the metaphysis , it will lead to
subperiosteal abscess
Fragments of necrotic bone
embedded in pus is known as
Sequestrum
Perisoteal reactive new (woven) bone
formation around necrotic sequestrum
is known as
Involucrum
a hole / tract formed in the bone
formation of draining sinus is known as
cloaca
Route of Infection of Pyogenic Spondyelitis
Arterial haematogenous
common locations of Pyogenic Spondyelitis
thoracic , lumbar
spontaneous bone fusion is known as
Ankylosis
Mention at least 4 COMPLICATIONS OF OSTEOMYELITIS
1- septic bacterial arthritis
2- chronic osteomyelitis
3- pathological fractures
4- septicaemia
5- SCC
6- amyloidosis
Initial focus of TB osteomyelitis in adults
metaphysis
Initial focus of TB osteomyelitis in children
epiphysis
pott’s disease location
lower thoracic & lumber vertebrae
mention at least 3 Complications of Pott’s Disease
1- cold abscess
2- rupture into soft tissue
3- angulations of spine
main vertebral deformity seen in pott’s disease
Kyphosis
what type of multinucleated giant cells are seen here
Langhan’s type of multinucleated giant cells
Identify what is 3 pointed by the arrows
Diagnose the case
-Multiple granulomas
seen in TB Spondylitis
fused bone or other hard tissue in seen in
septic arthritis
fused bone or other hard tissue is known as
Ankylosis
Multisystem disease caused by spirochete borrelia burgdorferi is known as
lyme disease
vectors of lyme disease
transmitted to man by ticks from deers
Viruses that causes viral arthritis
- hepatitis B
- rubella
- parovirus
mention the 3 non infectious arthritis
1- RA
2- Spondyloarthropathies
3-Juvenile arthritis