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I and I Midterm > Overview Of Immune > Flashcards

Overview Of Immune Flashcards

1
Q

Step 1 of immune response

A

Start immediate response with what we have innately or available

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2
Q

Step 2 of immune response

A

Innate

Recognize invader, adapt to it
Remember invader for future

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3
Q

Step 3 of immune response

A

Bring all components together to launch a full-fledged attack

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4
Q

Step 4 of immune response

A

Retract the attack once invader is gone

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5
Q

3 outcomes of complement
Define the hard one

A

Opsonization
Direct lysis
Chemotaxis / pro inflammatory effect
release C3a and C5a which activate immune cell recruitment

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6
Q

What 2 things reduce binding of complement

A

Capsule and peptidoglycan of gram positive

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7
Q

Innate immune is ____ line of defense

A

Second

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8
Q

Examples of phagocytes

A

Neutrophils and macrophages

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9
Q

Difference between macrophages and neutrophils

A

N = kill by eating

M = kill by eating AND release cytokines

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10
Q

Small proteins

A

Cytokines

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11
Q

Communicate between cells and trigger a bunch of immunological functions

A

Cytokines

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12
Q

Movement of a cell in a specific direction based on gradient of increasing or decreasing concentration of a chemical

A

Chemotaxis

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13
Q

______ that act as a chemoattractant to ______ migration of cells are called ___

A

Cytokines

Guide

CHEMOKINES

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14
Q

Classic example of a Pattern recognition receptor recognizing a Pathogen associated molecular pattern

A

TLR4 recognizing LPS

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15
Q

Purpose of cytokines

A

Amplification of immune response

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16
Q

Know what invader looks like and the right weapons to make because of______

A

Antigen Presenting Cells

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17
Q

What are antigens recognized by

A

B and T cells

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18
Q

Immune cells that process and present antigens to lymphocytes

Examples

A

APC

Macrophage, dendritic cells, B cells

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19
Q

_____ are best at antigen presenting

A

Dendritic

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20
Q

_____ are best at degrading

A

neutrophils

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21
Q

Do neutrophils, macrophages, and dendrites have the same function

A

Yes

22
Q

____ cells are good at amplifying immune response

A

Macrophages

23
Q

Does innate have memory

A

No

24
Q

T and B cells are _____

A

Lymphocytes

25
Q

Cytokines and APC do ____

A

Tell lymphocytes about the infection

26
Q

CD4 aka

A

Helper T cell

27
Q

CD8 aka

A

Cytotoxic T cell

Killer T cell

28
Q

T cell functions

A

Produce cytokines

Kill infected cells

Activate B cells

29
Q

Releases cytokines and chemokines and activates other cells (like B cells) Express CD4

A

Helper T

30
Q

Release proteins and kill cells infected with pathogen
And release cytokines

A

CD8 T cells

31
Q

B cell function

A

Make specific antibodies
Opsonization pathogen

32
Q

Specific antigens are aka

A

Immunoglobulins

33
Q

Humoral immunity is from? And its located where

A

B cell antibodies

In the blood

34
Q

____ immunity can fight against capsules with polysaccharide and lipids

A

Humoral

35
Q

______ is key in fighting INTRACELLULAR organisms

A

Cell-mediated

36
Q

Who has memory

A

B and T cells

37
Q

What are the anti inflammatory cytokines

A

IL10
TGFb

38
Q

Pro inflammatory cytokines

A

TNFα IL1 IL6

39
Q

Pro inflammatory chemokines

A

MCP1 aka CD40L

40
Q

When you have memory what is the response time compared to the first time you saw the pathogen

A

Much faster and much larger and better response

41
Q

Mature B and T cells that have not interacted with an antigen

A

Naive cells

42
Q

Effector cells

A

When B and T are activated and differentiate

43
Q

When are naive cells used

A

When we encounter a pathogen for the first time

44
Q

Vax are examples of

A

Immune memory

45
Q

When antibodies are administered from an outside source

A

Passive immunity

46
Q

Which onset is faster active immunity or passive

A

Passive

47
Q

Which lasts longer passive or active immunity

A

Active

48
Q

Influenza infection is an example of

A

Active immunity

49
Q

Vax is an example of

A

Active immunity

50
Q

IgA in breast milk is an example of

A

Passive immunity

51
Q

Maternal IgG crossing the placenta

A

Passive immunity

52
Q

Antibodies administered as medication
Ex: anti venom

A

Passive

I and I Midterm (19 decks)

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