Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CVRH Exam 1 > Overview of Blood Disorders: Red and White > Flashcards

Overview of Blood Disorders: Red and White Flashcards

1
Q

What cells come from myeloid progenitor cells?

A

Every blood cell except for lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the acronym for the abundance of WBC in the blood?

A

Never Let Monkeys Eat Bananas

Neutrophil lymphocyte monocyte eosinophil basophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Two different types of WBC disorders?

A

Leukopenia: too few
Proliferative: too many

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the most common cause of agranulocytosis (neutropenia)?

A

Drug toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is leukocytosis?

A

An increase in number of WBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common leukopenia?

A

Neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Four factors that affect peripheral blood leukocyte count?

A

Size of myeloid and lymphoid precursors and storage pools
Rate of release from storage pools
Proportion of cells that marginalize
Rate of extravasation of cells from blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is acute myeloid leukemia?

A

Increased number of immature WB cells in bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is myelodysplastic syndromes?

A

Increased immature WB cells in circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is chronic myeloproliferative disorder?

A

Increased mature WB cells in circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the major difference between lymphoma and leukemia?

A

Lymphoma: cancerous cells come from lymph
Leukemia: cancerous cells come from bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is anemia?

A

Reduction of total circulating red cell mass below normal limits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A low level of reduced glutathione is associated most directly with which of the following?

A

G6PD-deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does glutathione give RBCs?

A

Ability to protect themselves against oxidative injuries and lead to hemolysis (its a reducing agent)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What causes spherocytosis?

A

Inherited disorder caused by intrinsic defects in the red cell membrane skeleton that render the skeleton of RBCs spheroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where is the RBC mutation found in sickle cell anemia?

A

Beta-globin chain

17
Q

Four major types of hemolytic anemias?

A

Hereditary Spherocytosis
G6PD-deficiency disorder
Sickle cell disease
Thalassemia

18
Q

What does the inherited disorder thalassemia cause in RBCs structure?

A

Decreased synthesis of either alpha or beta chain adult hemoglobin

19
Q

What is associated with pernicious anemia?

A

B12 deficiency

20
Q

What is the proximate cause of anemia in vitamin B12 deficiency?

A

Folate (folic acid; B9)

21
Q

What causes chronic and acute immune thrombocytopenic purpura?

A

Auto antibodies IgG

acute is in children and may be drug induced

22
Q

What is Thrombotic thrombocytopenic purpura?

A

Pentad of hemolytic anemia, neuro defects, thrombocytopenia, microangiopathic hemolytic anemia, renal failure

CVRH Exam 1 (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions