Autonomic Drugs 2

Question 1

What does atropine do?

Answer 1

Competitive antagonist at all muscarinic receptors M1-M5

Question 2

What affect does atropine have on the heart?

Answer 2

Increases heart rate

Question 3

What does low does atropine cause?

Answer 3

Occupies pre-junctional muscarinic receptors, failure to turn off neuronal ACh release; PSNS affects

Question 4

What does moderate dose of atropine cause?

Answer 4

Sympathetic affects; blocking of PSNS

Question 5

What do high doses of atropine cause?

Answer 5

Hallucinations, blurred vision, cutaneous vasodilation, tachycardia, dry skin

Question 6

What sympathetic receptors are found in the eye?

Answer 6

Alpha 1

Question 7

What sympathetic receptors are found in peripheral vasculature?

Answer 7

Alpha 1

Question 8

What sympathetic receptors decrease insulin release?

Answer 8

Alpha 1

Question 9

What sympathetic receptors are found in genitals?

Answer 9

Alpha 1

Question 10

What sympathetic receptors are found in the lungs?

Answer 10

Beta 2

Question 11

What sympathetic receptors are found in cardiac muscle?

Answer 11

Beta 1

Question 12

What sympathetic receptors are responsible for vasodilation in SM?

Answer 12

Beta 2

Question 13

What sympathetic receptors are found increase insulin release?

Answer 13

Beta 2

Question 14

What sympathetic receptors cause relaxation in GI and uterine smooth muscle?

Answer 14

Beta 2

Question 15

What are alpha 2 receptors and their function?

Answer 15

Presynaptic in peripheral sympathetic nervous system; re-uptake norepinephrine as a negative feedback mechanism