Ovarian Female associated malignacies Flashcards
Ovaries are the females main source of
Hormones (estrogen and progesterone)
Ovarian age factors (2)
- Older females have a higher risk
- Rare in women younger than 40
Ovarian cancer Obesity risk factors: women with a body mass index of at least ___ have a higher risk of devolping ovaian cancer)
30
Ovarian cancer Reproductive history risk factors (3)
- Women who have been pregnat before 26
- Risk decresed with each full term pregnancy
- Higher risk for women who carried after age 35 or never carried a pregnacy to term
Ovarian cancer Risk factors (7)
- early menarche (menstration)
- smoking
- immunosupression
- family history of breast and ovaian
- pelvic inflammatory disease
- late menopause
- jewish decent
Mutations of ___ are responsible for most inherited ovaian cancers
BRCA
BRCA prevent cancer by
making proteins that keep cells from growing abnormaly (tumor suppressors)
Mutations in BRCA are 10 times more common in those who are
Ashkenazi jewish
Ovarian cancer Late stage clinical presentation (3)
- Abdominal or pelvic pain
- Abdominal distention
- Vague GI symptoms
What is used to screen women with high risk factors for ovarian cancer (2)
- Transvaginal US
- CA-125 blood tests
Ovarian cancer typically spreads to (3)
- adjacent organs
- peritoneal fluid
- lymph nodes
If Ovarian cancer radiation is considered ___ ___ must be covered with open field technique from ___ to ___
- peritoneal cavity
- diaphragm to pelvic floor
Tandem and ovoids are used to treat women who
still have a uterus
Tandem and ovoids treatment side effects (6)
- Vaginal irritaition
- fatigue
- diarrhea
- nasuea
- irritation of the bladder
- low blood counts
Vaginal cylinder is used to treat women who
Have had a hysterectomy
