Other drugs Flashcards
1
Q
Lofexidine
A
Alpha 2 agonist
2
Q
Buprenorphine
A
Partial agonist at mu receptor
3
Q
Naloxone
A
Pure opioid antagonist (will reverse mu, delta and kappa)
4
Q
Naltrexone
A
Long acting opioid antagonist, targeting endogenous opioid receptors (mu, delta and kappa), particularly mu
5
Q
Disulfram
A
Binds irreverisbly to ALDH causing acetaldehyde to accumulate following ingestion of alcohol
6
Q
Varenicline (Champix)
A
Nicotinic receptor partial agonist
7
Q
Acamprosate
A
NMDA glutamate receptor antagonise and positive allosteric modulator of GABA-A receptors ( effect on both receptors is indirect)
8
Q
Selegiline
A
Selective, irreversible inhibition of MAO-B (and MAO-A at higher doses)
9
Q
Sildefanil
A
Inhibits cGMP-specific phosphodiesterase type 5 (PDE5)
10
Q
Prazosin
A
Alpha-1 adrenergic receptor antagonist
