Dementia drugs Flashcards

1
Q

Donepezil

A

AChE-I (selective and reversible)

Diarrhoea, nausea, headache most common

Start 5mg daily, usual dose 10mg daily

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2
Q

Rivastigmine

A

AChE-I (reversible, non competitive), BuChE-I

Anorexia, dizziness, N&V, diarrhoea

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3
Q

Galantamine

A

AChE-I (competitive and reversible), nicotine receptor agonist

N&V

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4
Q

Memantine

A

NMDA receptor antagonist (non-competitive), 5-HT3 receptor antagonist

Dizziness, headache, fatigue, diarrhoea, gastric pain

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