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Pharmacology Part A > Mood stabiliser / antiepileptic MOA > Flashcards

Mood stabiliser / antiepileptic MOA Flashcards

1
Q

Valproate

A

GABA modulation (increases GABA in the brain), sodium channel inhibition, NMDA antagonist

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2
Q

Gabapentin

A

Binds to alpha 2 delta subunit of voltage gated calcium channels which reduces the release of certain neurotransmitters including glutamate and substance P, can help reduce neuronal excitability

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3
Q

Topiramate

A

GABA modulator, NMDA antagonist, Na channel stabiliser

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4
Q

Carbamazepine

A

Stabilises Na channels

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5
Q

Phenytoin

A

Stabilises Na channels

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6
Q

Lamotrigine

A

NMDA receptor modulation, stabilises Na channels and blocks calcium channels, some GABA modulation

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7
Q

Pregabalin

A

Binds to alpha-2-delta subunit of voltage gated calcium channels, reduces release of certain neurotransmitters including glutamate and substance P, help reduce neuronal excitability

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Pharmacology Part A (14 decks)

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