Other #2 Hypothalamus, Emotional States Flashcards
Location of Hypothalamus
- Inferior to the hypothalamic sulcus
- Superior to the pituitary gland
- Caudal to lamina terminalis
What structure does Hypothalamus continuous with?
Pituitary Gland
Composition of Hypothalamus
- Preoptic Area - Rostral
- Zones - Caudal to preoptic area. Run Medial - Lateral (Periventricular, Medial, Lateral)
Fibers of the Hypothalamus
- Medial Forebrain Bundle
- Dorsal Longitudinal Fasciculus
Hypothalamus receives input from? (7 structures) (*Harry’s Hippo Saw Amy’s Brain Power Taking Risks)
- Hippocampus (memory)
- Septal nuclei (Pleasure / Addiction)
- Amygdaloid (Emotion)
- Brainstem (Physiologic systems)
- Prefrontal cortex (executive function)
- Thalamus (sensory)
- Retina (Sensory)
Hypothalamus projects to?
- Amygdaloid
- Brainstem
- Thalamus
- Spinal Cord
Hypothalamus has intrinsic connections with?
Pituitary gland
Pituitary gland is divided into?
anterior - adenohypophysis
posterior - neurohypophysis
Function of Hypothalamus
Integrate autonomic response and endocrine function with behavior (homeostasis & behavior)
Most of the connections in Hypothalamus are?
Reciprocal
Which 6 basic physiologic processes does the hypothalamus regulate?
- Blood pressure and electrolyte composition
- Body Temperature
- Energy Metabolism
- Reproduction
- Emergency Response to stress
- Sleep-wake cycle
What are the 3 physiological mechanisms Underlying function?
- Receives sensory and context information
- Compares sensory information to biological set points
- Activates responses to restore homeostasis
Hypothalamus can be divided in which two areas?
- Caudolateral
- Rostromedial
Caudolateral Area
- Consists of the posterior (Mamillary) region and lateral zone
- Anxiety
- Increased activity of sympathetic division
Rostromedial Area
- Consists of the remaining anterior (supraoptic) and tuberal regions
- Contentment
- Increase activity of Parasympathetic
Temperature regulation
- External temperature: thermoreceptors in the skin
- Internal temperature: Thermoreceptors in the hypothalamus
When blood temperature is below normal
Thermoreceptors in the hypothalamus activates heat conservation and heat production
- Heat conservation mediated by autonomic pathways
- Heat production mediated by reticulospinal pathways
For water balance, information about the osmolarity of the blood is monitored by?
Osmolarity sensitive neurons in the hypothalamus
Example: When blood osmolarity is high
- Osmolarity sensitive neurons in the hypothalamus stimulate ADH
- ADH increases water resorption
A lesion of the hypothalamus could result in?
specific autonomic, endocrine & memory deficits