Osteoarthritis Flashcards

1
Q

What is limited in knee osteoarthritis?

A

Ambulation

Stair climbing

Getting up from chair

Carrying groceries

Heavy household chores

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2
Q

Where is hyaline cartilage found?

A

On articular surface of synovial joints

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3
Q

What does the hyaline cartilage function to do in the knee?

A

Bear and distribute compressive loads and to reduce friction between joint surfaces

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4
Q

What is the joint dependent on to function properly?

A

Cartilage

Bone

Capsule and ligament

Muscle and tendon

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5
Q

What occurs in subchondral bone?

A

Sclerosis (hardening)

Cyst formation

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6
Q

Osteochondrosis dissecans

A

Mimics OA (typically in younger population)

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7
Q

What percentage does genetics contribute to OA?

A

40-65%

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8
Q

What types of occupations have increased risk for OA?

A

Squatting kneeling combined with heavy lifting (plumbers, carpet layers, coal miners)

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9
Q

What risk factor does physical activity have for OA?

A

No evidence to have increased risk (vigorous activity can have higher risk)

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10
Q

What are the risk factors for knee OA?

A

Age

Sex (70% female/30% male)

Obesity

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11
Q

What type of injury significantly increases the risk of getting knee OA?

A

ACL or meniscus injury

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12
Q

Is there an increased risk of knee OA if you have Genu varum or valgum?

A

No (progresses OA but does not cause it)

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13
Q

How does leg length discrepancy contribute to knee OA?

A

People of leg length discrepancy of 1-2 cm are 2x more likely to develop OA

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14
Q

What is grade 0 of radiographic criteria?

A

No findings of OA

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15
Q

What is grade 1 of radiographic criteria?

A

Osteophytes of doubtful clinical significance

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16
Q

What is grade 2 of radiographic criteria?

A

Osteophytes with unimpaired joint space

17
Q

What is grade 3 of radiographic criteria?

A

Osteophytes with moderate joint space narrowing

18
Q

What is grade 4 of radiographic criteria?

A

Osteophytes with severe joint space narrowing and subchondral sclerosis

19
Q

What is the clinical and radio graphic classification for knee OA?

A

Pain in the knee with at least 1 of the following 3

Age >50

Morning stiffness <30 min

Crepitus and Osteophytes

20
Q

What is the source of pain in knee OA?

A

Synovium

Bone

Nerves

21
Q

Why is cartilage not likely the source of pain in knee OA?

A

Not innervated

22
Q

Are pain and severity of OA radiologic findings related?

A

Yes

23
Q

What are implications of Osteophytes present in the bone?

A

Severe pain and will likely need total joint replacement