Orthopedics Flashcards
Woven bone
Pathologic
Immature
Mature or normal bone
Lamellar
Bone resorption
Osteoclast
Maintains bone
Calcium and phosphorous homeostasis
Osteocyte
Builds the bone
Osteoblast
99% of Ca sequestered in bone
1% of Ca is in
ECF
50% free
50% bound with albumin
Prevent bone loss by inhibiting osteoclast resorption
Bisphosphonate
Bisphosphonate CI
Renal disease
Excretion
Bisphosphonate use may predispose to
Alendronate, Zonendronate
Jaw osteonecrosis
Drug that inc deposition of new bone by osteoblast and reduces resorption of bone osteoclast
Strontium ranelate
Recombinant protein form of parathyroid hormone
Effective anabolic agent for osteoporosis inc bone mass
Teriparatide
Stimulates osteoclast
Bone resorption
PTH
Stimulates osteoclast by stimulator
Osteoblast
Osteoblasts stimulate osteoclast by
RANKL
Type 1 collagen
Bone skin tendon