Orthopedics Flashcards
Woven bone
Pathologic
Immature
Mature or normal bone
Lamellar
Bone resorption
Osteoclast
Maintains bone
Calcium and phosphorous homeostasis
Osteocyte
Builds the bone
Osteoblast
99% of Ca sequestered in bone
1% of Ca is in
ECF
50% free
50% bound with albumin
Prevent bone loss by inhibiting osteoclast resorption
Bisphosphonate
Bisphosphonate CI
Renal disease
Excretion
Bisphosphonate use may predispose to
Alendronate, Zonendronate
Jaw osteonecrosis
Drug that inc deposition of new bone by osteoblast and reduces resorption of bone osteoclast
Strontium ranelate
Recombinant protein form of parathyroid hormone
Effective anabolic agent for osteoporosis inc bone mass
Teriparatide
Stimulates osteoclast
Bone resorption
PTH
Stimulates osteoclast by stimulator
Osteoblast
Osteoblasts stimulate osteoclast by
RANKL
Type 1 collagen
Bone skin tendon
Type 2 collagen
Cartilage
Type 3 collagen
Reticulin
Blood vessel
Type 4 collagen
Basement membrane
Annulus fibrosis is a type collage
1
Nucleus pulposus is collagen
Type II
Inc thoracic curvature
Kyophotic
Exaggerated curvature of lumbar spine
Lordosis
Cartilage model formed and replaced to bone
Endochondral bone formation
Direct bone formation
Intramembranous ossification
Slow ox fibers
Red fibers
First muscle type lost in rehab
Type 1 red
Fast glycolitic fiber
Type II
Type 1 osteoporosis
Post menopausal
Type 2
Old patients
Fracture
Selective estrogen receptor modulators
Estrogen agonist or antagonist depending on binding
Tamoxifen
Raloxifen
wear and tear arthritis
osteoarthritis
Radio findings of OA
Subchondral cyst
Osteophytes
Joint space narrowing
Eburnation
Most common primary sarcoma of bone
Lung metastasis
Osteosarcoma
Osteosarcoma radio
Sun burst of hair end pattern
Codmann’s triangle
Small round cell sarcoma
Ewing’s
Second most common malignant bone tumor in children
Ewing sarcoma
Moth eaten appearance
Onion skin and sunburet appearance
Ewing sarcoma