Esophagus Flashcards

1
Q

Esophagus develops during gestation

A

4th week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Failure of separation of dorsal foregut from laryngotracheobronchial tree during development

A

TEF fistula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Failure of recanalization of tubular lumen

A

Esophageal atresia, web, stenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

5-6cm

Extends from cricopharyngeus (C6) to thoracic inlet (T1)

A

Cervical esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
15cm
From TO (T1) to esophagea hiatus of diaphragm (T10)
A

Thoracic esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Short 5-6cm

Absent in patients with hiatal hernia or esophageal shortening from chronic inflammation

A

Abdominal esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cricopharyngeus (UES) innveration

A

recurrent laryngeal nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Functional zone not an anatomic structure

A

LES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Anatomic sites of esophageal narrowing

Most common sites of foreign body impaction

A

Aortic arch
left main stem Bronchus
Cricopharyngeus
Diaphragm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Esophageal wall layers

A

Mucosa
Submucosa
Muscularis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Esoohagus lacks this layer so healing is poor after insult

A

Serosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mucosa of esopahgus

A

Non keratinizing SSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Muscularis layer is divided into

A

Outer longitudinal

Inner circular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Upper 1/3 of esophageal muscle

Lower 2/3

A

striated

smooth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Esophageal landmark by endoscopic distance from incisor

UES

Thoracic inlet

Aortic arch/LMB

LES/GEJ

A

UES 15cm

TI 18cm

Aortic arch/LMB 25cm

LES/GEJ 40cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Upper 1/3 of esophagus blood supply

A

Inferior thyroid artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Middle 1/3 esophagus blood supply

A

Descending thoracic aorta

Bronchial arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Lower 1/3 esophagus blood supply

A

Left gastric artery

Inferior phrenic artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Parasympathetic inn to esophagus

A

Vagus nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Innervates cricopharyngeus and cervical region

A

recurrent laryngeal nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

sympathetic fibers for the esophagus arise from

A

Cervical

Thoracic chain ganglia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Contains nonsegmented network of lymphatics

A

Submucosa

Upper 2/3 cephalad drain
Lower caudad

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Site of cricopharyngeal weakness

Most common location to find pseudodiverticula or iatrogenic perforation

A

Killian’s triangle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

35 y/o female
progressive heartburn, regurgitation of undigested food
barium swallow: bird beak tapering of distal esoph
manometry reveals:

A

Achalasia
Lack of peristalsis
Failure of LES relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Strongest layer of esophagus

Primary importance for surgical repair

A

submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Most common esophageal motility disorder
25-60 years equal distribution
Aperistalsis
Failure of LES relaxation during swallowing
Not a primary disorder but neural degeneration

A

Achalasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Patients with achalasia present with

A

Progressive dysphagia to solids and liquids
Heartburn, chest paun
Regurgitation of undigested food
Techniques to ameliorate dysphagia by maintaining upright, keeping arms elevated over head, consuming liquid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Achalasia dx: finding

A

Barium swallow: bird beak with dilation if proximal segment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Dx mandatory to rule out obstructing mass or stricture

A

Esophagoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Manometry in achalasia reveals

A

lack of peristalsis and failure LES relxation

resting LES pressure may be normal or high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

UES pressure (resting)

A

50-70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

UES pressure (bolus)

A

12-14

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

LES pressure (resting)

A

10-20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Medical management of achalasia

A

Nitrates
Ca ch blocker
Botox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Symptomatic improvement but recurrence is high and risk of perforation at 5% in achalasia repair

A

Pneumatic dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Definitive therapy: achalasia

A

Heller myotomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Long standing severe achalasia

Dilated and non functional esophagus called

A

sigmoid esophagus

tx: esophagectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

smooth muscle degeneration
LES failure
disordered peristalsis of distal esophagus
esophageal dysmotility in 80% women 40-50
sparing of:

A

Scleroderma

proximal striated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Scleroderma s and sx

A

severe reflux esophagitis
dysphagia
scleroderma (calcinosis, Raynaud, esophageal dysmo, sclerodactyly, skin change, telangiectasia, renal impairment, pulmonary HTN)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Scleroderma dx: finding

A

Barium: dilated esophagus with DISTAL NARROWING

Manometry: dysmotility, aperistalsis of distal esophagus with inc LES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Medical mx of scleroderma

Sx

A

H2 blocker
PPI
HOB elevation

severe with loss of function (fundoplicariob and gastroplasty)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Primary motility disorder
Disordered high amplitude motility
Substernal chest pain radiating to neck or upper ex
Dysphagia with solid and liquid

A

Diffuse esophageal spasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

DES dx: finding

A

Barium: corkscrew esophagus and segmentation

Manometry: frequent, high amp, simultaneous contraction (>/= 20% of 10 simultaneous waveform)
LES normal

44
Q

DES medical mx

A

nitrate
Ca ch blocker
Botox

45
Q

Most common primary motility disorder
Chest pain, dysphagia
Manometry: continuous, high amp (>/=2 SD above normal) peristalsis

A

Nutcracker esophagus

Tx:
Nitrate
Ca ch blocker

Sx: Heller if nonrefractory

46
Q

Found at Killian’s triangle as a result of discoordination of UES relaxation and swallowing

A

Pharyngoesophageal

Zenker’s or Pulsion diverticulum

47
Q

Either pulsion (motility disorder) or traction bec of extra esophageal disease such as cancer or granulomatous infection

A

Middle esophageal diverticula

48
Q

Most commonly by motility d/o, achalasia
Associated with GERD
Within 10cm of GEJ

A

Epiphrenic diverticula

49
Q
Regurgitation
Halitosis
Aspiration
Chest pain
Dysphagia
Asymptomatic
A

Diverticulum

50
Q

Diverticulum dx

A

Barium
Manometry and pH studies: motility disorder with reflux
Esophagoscopy to rule out mechanical obstruction

51
Q

Sx for diverticula

A

Diverticulectomy with myotomy

Transoral stapled repair

52
Q

Congenital incomplete recanalization but may be acquired
Trans or mucosal and submucosal
Asymptomatic but sometimes dysphagia with solid food
Associated with GERD or IDA (Plummer Vinson)

A

Esophageal web, ring

53
Q

Ring at the GEJ due to GERD

A

Schatzki’s ring

54
Q

Majority of paraesophageal hernias are

A

Type I sliding hiatal

55
Q

Ulcer in sliding hiatal hernia
Lesser curve
Chronic blood loss but rarely with perforation

A

Cameron’s ulcer

56
Q

Borchardt’s triad

A

Severe chest pain
Painful retching without emesis
Inability to pass NGT

incarcerated paraesophageal hernia

57
Q
Incidenta on upper endoscopy or CT
Bowel sounds on chest
CXR air fluid level in chest
Coiled intrathoracic NGT
Barium swallow is dx
A

Esophageal hernia

58
Q

Chest
Contains GEJ with or without fundus
No volvulus

A

Type I Sliding Hiatal

59
Q

Abdomen
Contains fundus
Organoaxial volvulus

A

Type II rolling paraesophageal

60
Q

Chest
Contains GEJ, fundus, body
Organoaxial and mesoaxial volvulus

A

Type III mixed paraesophageal

61
Q

Chest
Contains GEJ, fundus abdominal organ
Organoaxial or mesoaxial volvulus

A

Type IV mixed paraesophageal

62
Q

Chest pain and paraesophageal hernia is emergency surgery bec of

A

risk of incarceration or strangulation

63
Q

Sliding hernia sx

A

Elective

64
Q

Preferred surgery for chronic hernia

A

Transthoracic

65
Q

Classic teaching for asymptomatic paraesophageal hernia

A

surgical repair for all

66
Q

Paraesophageal hernia repairs must be

A

hernia reduction
Sac excision
Tension free closure of crural defect

67
Q

Longitudinal mucosal tear near GEJ due to repeated retching and high intraluminal pressure

Common in alcoholics

Dx:

A

Mallory Weis tear

Endoscopy

68
Q

Most common cause of esophageal perforation

A

iatrogenic

69
Q

Spontaneous rupture of esophagus resulting from inc intraabdominal pressure against closed glottis during bouts of retching

Perforation by malignancy or infection (TB)

Elderly, delibiltated

A

Esophageal perforation

70
Q
Severe chest and back pain
Dyspnea
Dull percussion at left chest
Subcutaneous emphysems
Tachycardia
Hypotension
Severe sepsis with instability
A

Esophageal perforation

71
Q

Esoph perforation dx: finding

A

CXR: pneumomediastinum, subcutaneous emphysema, left hydropneumothorax, simple effusion

72
Q

Demostrates leak in esophageal rupture

A

Gastograffin swallow

73
Q

Localizes site of esophageal perforation

A

Esophagoscopy

74
Q

Esophageal rupture tx

A

Broad spec antibiotics
NPO
Fluid resuscitation
Drainage of effusion decompression of pneumothorax

75
Q

Esoph perforation operative therapy:

A

Irrigation and drainage of pleural cavity with primary repair of perforation
Reinforce with intercostal, pleural, pericardial flap

76
Q

Alkali agents cause

A

liquefactive necrosis

77
Q

Acids cause

A

coagulation necrosis

78
Q

Caustic injury mx

A

Dx: flexible esophagoscopy

Assess and secure airway
Do not neutralize agent
Observe if asymptomatic 
Mildd admit NPO for 1-2 days
Full thickness: NPO, TPN, antibiotic

Resect

79
Q

Caustic injury complications

A

stricture

SCC

80
Q

58 y/o,M
Hx of GERD
Endoscopy with biopsy: mild dysplasia

Ff up:

A

Endoscopic surveillance with biopsy every 2 years to monitor dysplasia

81
Q

Premalignant condition by intestinal metaplasia

Primary risk factor: GERD (5-10)

A

Barett’s

82
Q

If severe dysplasia is present perform

A

esophagectomy

83
Q

Resected Barrett’s specimen with severe dysplasia have adenocarcinoma:

A

20-50%

84
Q

SCC risk factors

A
Tobacco
Alcohol
Achalasia
Alkali injury 
Plummer Vinson
85
Q

Dx for SCC

A

Esophagoscopy with biopsy

staging: CT, PET, endoscopic uts

86
Q

Most common esophageal malignancy

A

Adenocarcinoma

87
Q

Adenocarcinoma rf

A

GERD

Barrett’sc

88
Q

Benign lesions and motility disorders appear

A

smooth narrowing

89
Q

Malignant lesions demonstrate

A

irregular apple core

appearance

90
Q

Stage I and IIA sx

T3NO

A

Surgery +/- neoadjuvant

91
Q

Stage IIB, III tx

A

chemoradiation (neoadjuvant) w/

surgery

92
Q

stage IV tx

A

palliation: esophageal stent

93
Q

Most common mortality and morbidity in postesophag

A

Postesohagectomy pneumonia

pulmo complication

94
Q

Incision: laparotomy, neck
Anastomosis: neck

A

Transhiatal

95
Q

Incision: laparotomy, right thoracotomy
anastomosis: chest

A

Ivor-Lewis

96
Q

Incision: left thoracotomy
Anastosmosis: chest

A

Thoracoabdominal

97
Q

Incision: laparotomy, right thoracotomy, neck
Anastomosis: neck

A

three hole

98
Q

Worst outcomes occur in leaks from

A

chest rather neck

99
Q

Majority of patients with esophageal ca present at stage

A

3

100
Q

Layer essential in anastomotic repair

A

submucosa

101
Q

Most common site of esophageal perforation during endoscopy

After repeated vomiting

A

Killian triangle

Distal thoracic esophagus

102
Q

Order of preference of conduit for esophageal reconstruction

A

Stomach>colon>jejunum

103
Q

45 y/o
progressive dysphagia to solid
first dx?

A

barium swallow

104
Q

determines resectability of esophageal malignancy

A

freedom from distant metastases or distal nodal involvement, ability to resect adjacent involved structure

105
Q

80 y/o
dysphagia with aspiration pneumonia
esophageal study contrast agent of choice?

A

Nonionic H20 soluble agent to minimize risk of pneumonitis

106
Q

Benefits of lap Heller and partial fundoplication vs left thoracoscopic myotomy for achalasia

A

Dec length of stay

Dec post op reflux