Orthomyxoviridae

Question 1

Is influenze a reportable disease?

Answer 1

Yes

Question 2

Orthomyxovirus has a ____ genome

Answer 2

segmented

Question 3

All Influenza viruses originally came from _____

Answer 3

aquatic birds

*water fowl

Question 4

True/False: Orthomyxovirus is fragile in environment

Answer 4

True

Question 5

Does Orthomyxovirus produce inclusion bodies?

Answer 5

no

Question 6

True/False: Every influenza virus hemagglutinates

Answer 6

True

Question 7

Antibodies to ____ proteins neutralize infectivity of the virions

Answer 7

Hemmaglutanin

Question 8

____ enhances the release of virions by cleaving sialic acid and lowers the viscosity of mucus membranes

Answer 8

Neurominidase

Question 9

True/False: Neurominidase neutralizes free virions

Answer 9

False

*only reduces the number of progeny virions released but does not neutralize virions

Question 10

There are ____ possible hemagglutinins and ____ possible neurominidases

Answer 10

16 hemaglutinins (H)

9 neurominidases (N)

Question 11

What are the different types of Influenzavirus and which one is the most important?

Answer 11

A- most important

B

C

Question 12

Influenza cells are ____ and kill the cells that they multiply in

Answer 12

cytolytic

Question 13

Major change involving hemagglutinin genes that results in genetic reassortment of two Influenza viruses that have infected the same cell

Answer 13

antigenic shift

Question 14

Minor change due to point mutations that alter the binding sites of protective antibodies of the hemagglutinin

Answer 14

antigenic drift

Question 15

What are the etiological agents of equine influenza?

Answer 15

Equine influenza A/H7N7

Equine Influenza A/H3N8- most important

Question 16

What does influenza cause in mammals?

Answer 16

Respiratory tract infections

Question 17

What does Influenza cause in Avian species?

Answer 17

Viremia- systemic infection

respiratory tract, GI tract, CNS

Question 18

What species is influenza deadly in?

Answer 18

Birds

Question 19

What type of infection does Equine influenza cause in horses?

Answer 19

Respiratory disease

*pneumonia

Question 20

Is equine influenza reportable?

Answer 20

yes

Question 21

True/False: mortality is rare in influenza, excepti in avian species

Answer 21

True

Question 22

How is equine influenza controlled?

Answer 22

Quarantine for 30 days

Question 23

Is there a vaccination for Equine influenza?

Answer 23

Yes

Question 24

What is the etiological agent in canine influenza?

Answer 24

Canine Influenze virus A [H3N8]

Question 25

Do we vaccinate for canine influenza?

Answer 25

Yes

Question 26

What kind of disease does canine influenza cause in dogs?

Answer 26

highly contagious respiratory disease

Question 27

With swine influenza there is a short term ___ stage

Answer 27

carrier

Question 28

What is the etiological agent of swine influenza?

Answer 28

Influenza A virus subtype H1N1

Question 29

The severity of Influenza in swine is determined by which nematode?

Answer 29

Ascaris suum

Question 30

Is there a vaccine for swine influenza?

Answer 30

yes

Question 31

What are the other names for Avian influeza virus A

Answer 31

bird flu

fowl plague

Question 32

What is the highly pathogenic etiological agent in avian influenza virus A

Answer 32

Avian influenza A virus [HPAI]

*Kills majority of birds that it infects

Question 33

What are the reservoir hosts for avian influenza virus A?

Answer 33

water fowl

Question 34

How are all influenza viruses transmitted?

Answer 34

aerosolization

Question 35

What is the control for Avian influenza type A?

Answer 35

quarantine and depopulation

Question 36

What is the important difference between Newcastle disease and Bird flu?

Answer 36

Newcastle- we vaccinate

Bird flu- no vaccination