**orthomolecular/mushrooms Flashcards

1
Q

Co Q10 also known as

A

ubiquinone

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2
Q

Co q10 soluble in what

A

fat

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3
Q

2 pain functions coQ10

A

mitochondrial energy synthesis

antioxidant in cell membranes & lipoproteins

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4
Q

foods containing Q10

A

meat
poultry
fish
nuts

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5
Q

deficiency Q10 found in individuals with

A

diabetes
cancer
congestive heart failure
parkinsons

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6
Q

5 ways Q10 improves CVD

A

inhibits atherosclerosis:

  • inhibits LDL oxidation
  • prevents monocyte recruitment to atherosclerotic plaque

congestive heart failure - improves cardiac function
MI - decreases post-infarct heart damage
Angina - ^ exercise tolerance, reduced freq attacks
Hypertension - reduces systolic & diastolic BP

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7
Q

which enzyme synthesises Q10 & cholesterol

A

HMG CoA reductase

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8
Q

4 other therapeutic uses Q10

A

reduces muscle pain in statins
improves gum disease
slows parkinson
anti-ageing

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9
Q

alpha lipoid acid soluble in what

A

water and fat

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10
Q

endogenous ALA essential for what

A

mitochondrial energy production - ATP

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11
Q

exogenous ALA does what

A

antioxidant (can be pro)

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12
Q

ALA - ATP production, antioxidant, what other 3 actions

A

increases action of insulin
increases glutathione production
antiinflamm

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13
Q

how is ALA helpful in diabetes

A

increases insulin sensitivity/glucose disposal

reduces insulin resistance\reduces peripheral neuropathy

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14
Q

ala may compete with what for absorption

A

biotin

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15
Q

ALA may slow what developing

A

dementia

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16
Q

3 ways glucosamine produced

A

synthesised by body
derived from marine exoskeletons
synthetically produced

17
Q

form of glucosamine with best bioavailability

A

glucosamine sulphate

18
Q

which form of glucosamine good for leaky gut if can’t use glutamine

A

N-Acetyl Glucosamine (NAG)

19
Q

2 therapeutic uses for N Acetyl Glucosamine

A

IBD

RA

20
Q

how does glucosamine sulphate slow progression of osteoarthritis by 54%

A

stimulates metabolism chondrocytes

inhibits production of inflame mediators

21
Q

how does chondroitin sulphate protect cartilage

A

reduces degrading enzymes
reduces inflamm action
increases synthesis hyalauronic acid

22
Q

which condition might chondroitin sulphate worsen

A

asthma

23
Q

2 conditions Methyl sulfonylmethane helps

A

osteoarthritis
CVD - reduces homocysteine (methyl donor)
- reduces lipid oxidation

24
Q

betaine anhydrous found in which foods

A

beetroot
spinach
wine

25
Q

2 conditions betaine anhydrous helps

A

hyperhomocysteineamia - reduces 20-30%

liver disease

26
Q

Dimethyl glycine water/fat soluble

A

water

27
Q

condition DMG (dimethyl glycine) might help

A

autism

28
Q

where is phosphatidyl serine found

A

most foods
oily fish
organ meats
beans

29
Q

phosphatidly serine soluble in what

A

fat

30
Q

what is most abundant phospholipid in human brain, v important in neuronal membrane functions

A

phosphatidyl serine

31
Q

3 conditions phosphatidyl serine helps

A

AD - improves cognitive function, ^ NT levels
age-related cognitive impairment
dementia

32
Q

cordyceps effect on blood

A

lowers blood glucose, plasma triglycerides, cholesterol

33
Q

reishi effect on blood

A

lowers BP

reduces platelet aggregation

34
Q

3 actions of shiitake

A

anti-tumour
cholesterol-lowering
virus inhibiting

35
Q

side effects shiitake

A

abdominal discomfort
siitake dermatitis
eosinophilia
photosensitivity