**orthomolecular/mushrooms Flashcards
Co Q10 also known as
ubiquinone
Co q10 soluble in what
fat
2 pain functions coQ10
mitochondrial energy synthesis
antioxidant in cell membranes & lipoproteins
foods containing Q10
meat
poultry
fish
nuts
deficiency Q10 found in individuals with
diabetes
cancer
congestive heart failure
parkinsons
5 ways Q10 improves CVD
inhibits atherosclerosis:
- inhibits LDL oxidation
- prevents monocyte recruitment to atherosclerotic plaque
congestive heart failure - improves cardiac function
MI - decreases post-infarct heart damage
Angina - ^ exercise tolerance, reduced freq attacks
Hypertension - reduces systolic & diastolic BP
which enzyme synthesises Q10 & cholesterol
HMG CoA reductase
4 other therapeutic uses Q10
reduces muscle pain in statins
improves gum disease
slows parkinson
anti-ageing
alpha lipoid acid soluble in what
water and fat
endogenous ALA essential for what
mitochondrial energy production - ATP
exogenous ALA does what
antioxidant (can be pro)
ALA - ATP production, antioxidant, what other 3 actions
increases action of insulin
increases glutathione production
antiinflamm
how is ALA helpful in diabetes
increases insulin sensitivity/glucose disposal
reduces insulin resistance\reduces peripheral neuropathy
ala may compete with what for absorption
biotin
ALA may slow what developing
dementia
3 ways glucosamine produced
synthesised by body
derived from marine exoskeletons
synthetically produced
form of glucosamine with best bioavailability
glucosamine sulphate
which form of glucosamine good for leaky gut if can’t use glutamine
N-Acetyl Glucosamine (NAG)
2 therapeutic uses for N Acetyl Glucosamine
IBD
RA
how does glucosamine sulphate slow progression of osteoarthritis by 54%
stimulates metabolism chondrocytes
inhibits production of inflame mediators
how does chondroitin sulphate protect cartilage
reduces degrading enzymes
reduces inflamm action
increases synthesis hyalauronic acid
which condition might chondroitin sulphate worsen
asthma
2 conditions Methyl sulfonylmethane helps
osteoarthritis
CVD - reduces homocysteine (methyl donor)
- reduces lipid oxidation
betaine anhydrous found in which foods
beetroot
spinach
wine