**orthomolecular/mushrooms Flashcards

1
Q

Co Q10 also known as

A

ubiquinone

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2
Q

Co q10 soluble in what

A

fat

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3
Q

2 pain functions coQ10

A

mitochondrial energy synthesis

antioxidant in cell membranes & lipoproteins

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4
Q

foods containing Q10

A

meat
poultry
fish
nuts

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5
Q

deficiency Q10 found in individuals with

A

diabetes
cancer
congestive heart failure
parkinsons

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6
Q

5 ways Q10 improves CVD

A

inhibits atherosclerosis:

  • inhibits LDL oxidation
  • prevents monocyte recruitment to atherosclerotic plaque

congestive heart failure - improves cardiac function
MI - decreases post-infarct heart damage
Angina - ^ exercise tolerance, reduced freq attacks
Hypertension - reduces systolic & diastolic BP

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7
Q

which enzyme synthesises Q10 & cholesterol

A

HMG CoA reductase

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8
Q

4 other therapeutic uses Q10

A

reduces muscle pain in statins
improves gum disease
slows parkinson
anti-ageing

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9
Q

alpha lipoid acid soluble in what

A

water and fat

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10
Q

endogenous ALA essential for what

A

mitochondrial energy production - ATP

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11
Q

exogenous ALA does what

A

antioxidant (can be pro)

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12
Q

ALA - ATP production, antioxidant, what other 3 actions

A

increases action of insulin
increases glutathione production
antiinflamm

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13
Q

how is ALA helpful in diabetes

A

increases insulin sensitivity/glucose disposal

reduces insulin resistance\reduces peripheral neuropathy

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14
Q

ala may compete with what for absorption

A

biotin

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15
Q

ALA may slow what developing

A

dementia

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16
Q

3 ways glucosamine produced

A

synthesised by body
derived from marine exoskeletons
synthetically produced

17
Q

form of glucosamine with best bioavailability

A

glucosamine sulphate

18
Q

which form of glucosamine good for leaky gut if can’t use glutamine

A

N-Acetyl Glucosamine (NAG)

19
Q

2 therapeutic uses for N Acetyl Glucosamine

20
Q

how does glucosamine sulphate slow progression of osteoarthritis by 54%

A

stimulates metabolism chondrocytes

inhibits production of inflame mediators

21
Q

how does chondroitin sulphate protect cartilage

A

reduces degrading enzymes
reduces inflamm action
increases synthesis hyalauronic acid

22
Q

which condition might chondroitin sulphate worsen

23
Q

2 conditions Methyl sulfonylmethane helps

A

osteoarthritis
CVD - reduces homocysteine (methyl donor)
- reduces lipid oxidation

24
Q

betaine anhydrous found in which foods

A

beetroot
spinach
wine

25
2 conditions betaine anhydrous helps
hyperhomocysteineamia - reduces 20-30% | liver disease
26
Dimethyl glycine water/fat soluble
water
27
condition DMG (dimethyl glycine) might help
autism
28
where is phosphatidyl serine found
most foods oily fish organ meats beans
29
phosphatidly serine soluble in what
fat
30
what is most abundant phospholipid in human brain, v important in neuronal membrane functions
phosphatidyl serine
31
3 conditions phosphatidyl serine helps
AD - improves cognitive function, ^ NT levels age-related cognitive impairment dementia
32
cordyceps effect on blood
lowers blood glucose, plasma triglycerides, cholesterol
33
reishi effect on blood
lowers BP | reduces platelet aggregation
34
3 actions of shiitake
anti-tumour cholesterol-lowering virus inhibiting
35
side effects shiitake
abdominal discomfort siitake dermatitis eosinophilia photosensitivity