**Disease Triggers Flashcards
Hormone-like substances that play a large role in immune & inflamm reactions
Histamine a Prostaglandins Cytokines Lymphokines Interferons
Immunoglobulin ass with true allergies
IgE
Ex of IgE hypersensitivity reactions
Airway closure
Tongue & throat oedema
Urticaria
Anaphylaxis
Poss reasons for allergy increase
More Exposure to 1 type food Exp to preservatives, artificial colourings etc Chemical pollution Early baby weaning
Less
Diet diversity
Digestion
Most common allergy sx
Sneezing Runny nose Itchy ears Coughing sob Sinus probs Sore palate Wheezing Urticaria
Allergic conditions
Asthma Eczema Headaches Lethargy Coeliac
7 pathways mediating food intolerances
enzyme defects pharmacological reactions toxic reaction additives in foods salicylates in foods histamine reaction IgG reactions
6 negative effects smoking
cancer - mouth/throat/lung/liver/kidney COPD weakens immune sx slow wound healing earlier menopause ^ risk birth defects
3 polysymptomatic disorders that could be caused by toxic chemical exposure
sick building syndrome
chronic fatigue syndrome
gulf war syndrome
which body system does lead affect
CNS
3 sources of mercury toxicity
fish consumption
dental amalgams
vaccinations
which tripeptide does mercury bind to
glutathione
where does mercury often acct,ulate
heart = ^BP, CVD
brain - AD
long term effects amphetamines
malnutrition psychosis insomnia violence brain damage
longterm effects cannabis
respiratory illness
lowers motivation, brain function
mental disorders
longterm effects cocaine
insomnia depression anxiety psychosis eating disorders hallucinations
OCP serious side effects aches
ACHES Ab pain chest pain headaches - bad swelling - legs contact GP! liver/stroke/blood clots/cvd!
OCP increases risk of what by 3-6 fold
thromboembolism
soothing further increases this
micronutrients OCP prevents
lots of B6 & Mg
also B vits (not b5), & C
OCP ^ serum levels of
Cu & Vit A
when are POPS (progesterone only pills) recommended instead of OCP
35+
^BP
smoker
blood clots
when is OCP not even at all
family history - serious heart/liver disease
cancer - breast/uterus
3 common side effects ant-b’s
upset stomach
diarrhoea
thrush
severe antibiotic side effects
allergy
colitis
kidney/liver problems
bone marrow problems
children prescribed anti-B’s before 1 are twice as likely to develkop
asthma
what is produced by cox enzymes,
promote pain, inflame & fever
supports blood clotting
and protects stomach lining from acid
prostaglandins
which cox? GI mucosa integrity platelet function renal function prostaglandins
1
which cox? pain fever inflame prostaglandins
2
how to NSAIDS work
block COX enzymes, reduce prostaglandins, reducing inflamm, pain, fever
common side effects NSAIDS
nausea D&V constipation low appetite rash dizziness drowsiness oedema
serious side effects NSAIDs
allergy ulcers intestinal bleeding perforation stomach/intestines ^ MI?stroke risk
which enzyme to statins inhibit
HMG-CoA reductase
3 effects statins
reduces cholesterol synthesis
^ synthesis LDL receptors
Increases LDL clearance from blood
side effects statins
muscle pain (rhabdomyolysis) liver damage - check reg digestive issues headache rash
