Orlistat Flashcards
1
Q
What are the indications for orlistat?
A
indicated for weight loss in over 18 year olds who are overweight BMI>28
2
Q
How should it be taken?
A
with a mildly hypocaloric lower-fat diet
3
Q
What is it C/I in?
A
- Hypersensitivity to the active substance or to any of the excipients
- people with chronic malabsorption syndrome
- people with cholestasis
- concurrent tx with ciclosporin
- P/BF
4
Q
What dosage should pts take?
A
one 60mg capsule TDS - take with water immediately before or during or up to one hour after each meal
no more than 3 should be taken in 24 hours
if a meal is missed or contains no fat - do not take orlistat
5
Q
how long should tx not exceed?
A
6 months
6
Q
Any interactions?
A
- indirectly reduces oral contraceptives and leads to unwanted pregnancies
- acarbose
- amiodarone - decrease levels of amiodarone
- hypothyroidism
