Oral Pathology Chapter 17 Flashcards
What disease is a group of conditions characterized by the deposition of an extracellular, proteinaceous substance termed amyloid?
Amyloidosis
What does vitamin A deficiency potentially cause?
Blindness
What does vitamin B1 (Thiamine) deficiency potentially cause?
Beriberi
What does vitamin B2 (Riboflavin) deficiency potentially cause (2)?
Angular Cheilitis and glossitis
What does vitamin B3 (Niacin) deficiency potentially cause (2)?
Pellagra and dermatitis
What does vitamin B6 (pyridoxine) deficiency potentially cause?
Lack AA synthesis
What does vitamin C deficiency potentially cause?
Scurvy
What does vitamin D deficiency potentially cause (2)?
- Rickets and 2. Osteomalacia
What does vitamin E (alpha tocopherol) deficiency potentially cause?
Antioxidant deficiency
What does vitamin K deficiency potentially cause?
Coagulopathy
What disease causes a bald, red tongue and is related to menorrhagia?
Iron Deficiency Anemia
If a tongue is really big and red, what disease comes to mind?
Pernicious anemia
What two oral manifestations appear in Iron Deficiency Anemia?
- Angular Cheilitis and 2. Atrophic Glossitis
What lab findings are suggestive of Iron Deficiency Anemia?
Hypochromatic microcytic RBCs
What pathology is associated with Iron-deficiency Anemia, Glossitis and Dysphagia?
Plummer-Vinson Syndrome
What demographic group is prone to Plummer-Vinson Syndrome?
Scandinavian women between 30 and 50
What is a sign outside the mouth that a patient may have Plummer-Vinson Syndrome?
Spoon-shaped nails (koilonychia)
What disease is caused by poor absorption of Cobalamin (Vitamin B12)?
Pernicious Anemia
What causes the poor absorption of Cobalamin as is seen in Pernicious Anemia?
Patients lack intrinsic factor due to autoimmune disorder of parietal cells of the stomach
What is a common oral manifestation of Pernicious Anemia?
Atrophic Glossitis
What typically causes Gigantism?
Pituitary adenoma before the closure of the epiphyseal plates
What is an oral sign of Gigantism?
Generalized Macrodontia
What causes Acromegaly?
Overproduction of growth hormone after epiphyseal plates have sealed
What does the extra growth seen in Acromegaly cause in terms of dental side effects?
Increased mandible growth leading to diasthma formation and macroglossia
