Oral Pathology Chapter 12 Flashcards

1
Q

What is the most common tumor of the oral cavity?

A

Fibroma

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2
Q

What type of proliferation is a fibroma?

A

Hyperplasia

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3
Q

What fibrous tumor can be found on the gingiva and is not related to irritation?

A

Giant cell fibroma

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4
Q

What lesion is found bilaterally on the lingual gingiva?

A

Retrocuspid papilla

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5
Q

What is the tumor-like hyperplasia of fibrous connective tissue called that can result from the flange of an ill-fitting denture?

A

Epulis Fissuratum

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6
Q

What is the name of the tumor-like hyperplasia of fibrous connective tissue?

A

Inflammatory Fibrous Hyperplasia (IFH)

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7
Q

What is the condition called that occurs when a patient wears their denture 24/7?

A

Inflammatory Papillary Hyperplasia (IPH)

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8
Q

What results from the overproduction of hyaluronic acid by fibroblasts and has a 2/3 occurrence on the gingiva and 1/3 occurrence on the hard palate?

A

Oral focal mucinosis

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9
Q

What is the scientific name for “pregnancy tumor”?

A

Pyogenic granuloma

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10
Q

What causes “pregnancy tumor”?

A

Trauma

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11
Q

Where is the most likely location of “pregnancy tumor”?

A

Gingiva

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12
Q

What is the old Latin term for “pregnancy tumor”?

A

Granuloma gravidarum

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13
Q

How should treatment proceed on a pregnant patient with “pregnancy tumor”?

A

It should be delayed unless functional or esthetic problems develop.

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14
Q

What is the most likely cause of a purple growth on the gingival tissue?

A

Peripheral giant cell granuloma

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15
Q

What effect can PGCGs have on the mouth?

A

They can cause the resorption of bone

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16
Q

What is the name of the mass that appears on the gums and tends to have a whitish appearance?

A

Peripheral Ossifying Fibroma

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17
Q

What two growths occur exclusively on the gingiva or alveolar ridge?

A
  1. Peripheral Ossifying Fibromas and 2. Perpherial Giant Cell Granulomas
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18
Q

What growth is associated with the incisor-cuspid region?

A

Peripheral Ossifying Fibromas

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19
Q

What is a benign tumor of fat called?

A

Lipoma

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20
Q

What is the most common mesenchymal neoplasm?

A

Lipoma

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21
Q

What is the most common site of growth for lipomas?

A

Buccal mucosa

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22
Q

Should trauma be caused around the 1st mandibular premolar region, what could result?

A

Traumatic Neuroma

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23
Q

What type of growth is a benign neural tumor typically found on the face?

A

Palisaded Encapsulated Neuroma (PEN)

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24
Q

What percentage of PEN is found of the face?

A

90%

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25
Q

What is the average age of a PEN patient?

A

50

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26
Q

What symptom is a characteristic feature of the neurofibromatosis type II (NF2)?

A

Bilateral Schwannomas of the auditory-vestibular nerve

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27
Q

What is the most common oral site of Schwannomas?

A

Tongue

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28
Q

What is the term that describes streaming fascicles of spindle-shaped Schwann cells which form a palisaded arrangement around central acellular, eosinophilic areas?

A

Antoni A

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29
Q

What is the name of the disorganized form of Schwannomas?

A

Antoni B

30
Q

What are organized spindle-shaped Schwann cells called in Schwannomas?

A

Verocay bodies

31
Q

What is the most common type of peripheral nerve neoplasm?

A

Neurofibroma

32
Q

What is the most common location of a neurofibroma (extra orally)?

A

Skin

33
Q

What is the most common two locations of a neurofibroma intraorally?

A

Tongue and buccal mucosa

34
Q

What is the biggest concern with neurofibromas?

A

That the patient has neurofibromatosis

35
Q

What is the name of the disease that has the feeling of a “bag of worms” and has six characteritic features that can be used to identify it?

A

Neurofibromatosis Type I

36
Q

What is the other term given to NF1?

A

Von Recklinghausen’s disease of the skin

37
Q

What is pathognomonic for NF1?

A

Plexiform variant of NF

38
Q

What does a plexiform variant of NF feel like?

A

Bag of worms

39
Q

What ratio of patients have the mild form of NF1?

A

2/3

40
Q

What is the name of the diagnostic markings that appear like light birthmarks?

A

Cafe au lait

41
Q

What shape do markings suggestive of NF1 appear?

A

Coast of California

42
Q

What is the name of the markings in the axillary region called?

A

Crowe’s Sign

43
Q

What is the name of the problem with the second cranial nerve experienced in NF1 patients?

A

Optic Glioma

44
Q

What are the nodules called that arise on the eyes in NF1 (two names)?

A
  1. Iris Hamartomas and 2. Lisch nodules
45
Q

What pathology is associated with “acoustic neuromas”?

A

Schwannomas

46
Q

If a patient has parathyroid tumors, pituitary tumors, pancreatic tumors, adrenal gland tumors, thyroid tumors and mucosal neuromas in the oral cavity, what do they likely have?

A

Multiple Endocrine Neoplasia, Type 2B (MEN 2B)

47
Q

What is often the first symptom of MEN 2B?

A

Oral mucosal neuromas

48
Q

What percentage of MEN 2B patients develop pheochromocytomas?

A

50%

49
Q

What percentage of MEN 2B patients develop medullary carcinoma of the thyroid gland?

A

90%

50
Q

What disease is associated with the first year of life, has a predilection for the anterior maxilla and is clinically blue or black?

A

Melanotic neuroectodermal tumor of infancy

51
Q

Patients that have Melanotic neuroectodermal tumors of infancy exhibit what in their urine?

A

High levels of vanillylmandelic acid

52
Q

What pathology is a swelling, most often in the dorsal of the tongue, that exhibits pseudoepitheliomatous hyperplasia?

A

Granular Cell Tumor

53
Q

What dying technique is associated with identifying Granular Cell Tumors and comes back positive?

A

S-100

54
Q

What pathology is associated with a negative S-100 test, is found in newborns, occurs 90% of the time in females and is 3X more common on the maxillary ridge?

A

Congenital Epulis

55
Q

What is the most common tumor of infancy, is most common in whites and females and is most often located on the head and neck?

A

Hemangioma

56
Q

What type of Hemangioma is associated with not blanching and remaining red in color?

A

Capillary

57
Q

What type of Hemangioma is associated with blanching and tends to be darker red to purple in color?

A

Cavernous

58
Q

What disease is associated with persistence of vascular plexus around the cephalic portion of the neural tube and is associated with a port wine stain?

A

Sturge-Weber Angiomatosis

59
Q

What is the scientific name of port wine stains?

A

Nevus Flammeus

60
Q

What nerve is associated with Sturge-Weber Angiomatosis?

A

One/more segments of the trigeminal nerve

61
Q

What nerve is associated with risk for full symptoms of Sturge-Weber Angiomatosis?

A

Ophthalmic branch

62
Q

Besides Nevus Flammeus, what other symptom presents in Sturge-Weber Angiomatosis?

A

Leptomeningeal angiomas

63
Q

In addition to other symptoms, which disease is associated with convulsive disorders, mental retardation, contralateral hemiplagia and hypervascular changes in ipsilateral intraoral mucosa?

A

Sturge-Weber Angiomatosis

64
Q

What disease appears as “frog eggs” or “tapioca pudding” and is frequently found in the mouth?

A

Cavernous Lymphangiomas

65
Q

What pathology is associated with smooth muscle benign tumors?

A

Leiomyoma

66
Q

What is the pathology that is very rare, has a predilection for the head and neck and is a neoplasm of skeletal muscle?

A

Rhabdomyoma

67
Q

What percentage of soft tissue sarcomas in children are Rhabdomyomas?

A

60%

68
Q

How do primary malignancies likely spread?

A

Via Lymphatics

69
Q

Where do malignancies typically spread from the lower body?

A

The lungs

70
Q

How might metastasis spread past the lung?

A

Through Batson’s plexus

71
Q

What are the first and second most common sites of metastasis of soft tissue in the mouth?

A
  1. Gingiva (50%) and 2. Tongue (25%)
72
Q

When malignancies spread to soft tissues in the oral cavity, what portion spreads to soft tissue and which portion spreads to bone?

A

2/3 soft tissue and 1/3 into bone