Oral Pathology Chapter 12 Flashcards
What is the most common tumor of the oral cavity?
Fibroma
What type of proliferation is a fibroma?
Hyperplasia
What fibrous tumor can be found on the gingiva and is not related to irritation?
Giant cell fibroma
What lesion is found bilaterally on the lingual gingiva?
Retrocuspid papilla
What is the tumor-like hyperplasia of fibrous connective tissue called that can result from the flange of an ill-fitting denture?
Epulis Fissuratum
What is the name of the tumor-like hyperplasia of fibrous connective tissue?
Inflammatory Fibrous Hyperplasia (IFH)
What is the condition called that occurs when a patient wears their denture 24/7?
Inflammatory Papillary Hyperplasia (IPH)
What results from the overproduction of hyaluronic acid by fibroblasts and has a 2/3 occurrence on the gingiva and 1/3 occurrence on the hard palate?
Oral focal mucinosis
What is the scientific name for “pregnancy tumor”?
Pyogenic granuloma
What causes “pregnancy tumor”?
Trauma
Where is the most likely location of “pregnancy tumor”?
Gingiva
What is the old Latin term for “pregnancy tumor”?
Granuloma gravidarum
How should treatment proceed on a pregnant patient with “pregnancy tumor”?
It should be delayed unless functional or esthetic problems develop.
What is the most likely cause of a purple growth on the gingival tissue?
Peripheral giant cell granuloma
What effect can PGCGs have on the mouth?
They can cause the resorption of bone
What is the name of the mass that appears on the gums and tends to have a whitish appearance?
Peripheral Ossifying Fibroma
What two growths occur exclusively on the gingiva or alveolar ridge?
- Peripheral Ossifying Fibromas and 2. Perpherial Giant Cell Granulomas
What growth is associated with the incisor-cuspid region?
Peripheral Ossifying Fibromas
What is a benign tumor of fat called?
Lipoma
What is the most common mesenchymal neoplasm?
Lipoma
What is the most common site of growth for lipomas?
Buccal mucosa
Should trauma be caused around the 1st mandibular premolar region, what could result?
Traumatic Neuroma
What type of growth is a benign neural tumor typically found on the face?
Palisaded Encapsulated Neuroma (PEN)
What percentage of PEN is found of the face?
90%
What is the average age of a PEN patient?
50
What symptom is a characteristic feature of the neurofibromatosis type II (NF2)?
Bilateral Schwannomas of the auditory-vestibular nerve
What is the most common oral site of Schwannomas?
Tongue
What is the term that describes streaming fascicles of spindle-shaped Schwann cells which form a palisaded arrangement around central acellular, eosinophilic areas?
Antoni A
What is the name of the disorganized form of Schwannomas?
Antoni B
What are organized spindle-shaped Schwann cells called in Schwannomas?
Verocay bodies
What is the most common type of peripheral nerve neoplasm?
Neurofibroma
What is the most common location of a neurofibroma (extra orally)?
Skin
What is the most common two locations of a neurofibroma intraorally?
Tongue and buccal mucosa
What is the biggest concern with neurofibromas?
That the patient has neurofibromatosis
What is the name of the disease that has the feeling of a “bag of worms” and has six characteritic features that can be used to identify it?
Neurofibromatosis Type I
What is the other term given to NF1?
Von Recklinghausen’s disease of the skin
What is pathognomonic for NF1?
Plexiform variant of NF
What does a plexiform variant of NF feel like?
Bag of worms
What ratio of patients have the mild form of NF1?
2/3
What is the name of the diagnostic markings that appear like light birthmarks?
Cafe au lait
What shape do markings suggestive of NF1 appear?
Coast of California
What is the name of the markings in the axillary region called?
Crowe’s Sign
What is the name of the problem with the second cranial nerve experienced in NF1 patients?
Optic Glioma
What are the nodules called that arise on the eyes in NF1 (two names)?
- Iris Hamartomas and 2. Lisch nodules
What pathology is associated with “acoustic neuromas”?
Schwannomas
If a patient has parathyroid tumors, pituitary tumors, pancreatic tumors, adrenal gland tumors, thyroid tumors and mucosal neuromas in the oral cavity, what do they likely have?
Multiple Endocrine Neoplasia, Type 2B (MEN 2B)
What is often the first symptom of MEN 2B?
Oral mucosal neuromas
What percentage of MEN 2B patients develop pheochromocytomas?
50%
What percentage of MEN 2B patients develop medullary carcinoma of the thyroid gland?
90%
What disease is associated with the first year of life, has a predilection for the anterior maxilla and is clinically blue or black?
Melanotic neuroectodermal tumor of infancy
Patients that have Melanotic neuroectodermal tumors of infancy exhibit what in their urine?
High levels of vanillylmandelic acid
What pathology is a swelling, most often in the dorsal of the tongue, that exhibits pseudoepitheliomatous hyperplasia?
Granular Cell Tumor
What dying technique is associated with identifying Granular Cell Tumors and comes back positive?
S-100
What pathology is associated with a negative S-100 test, is found in newborns, occurs 90% of the time in females and is 3X more common on the maxillary ridge?
Congenital Epulis
What is the most common tumor of infancy, is most common in whites and females and is most often located on the head and neck?
Hemangioma
What type of Hemangioma is associated with not blanching and remaining red in color?
Capillary
What type of Hemangioma is associated with blanching and tends to be darker red to purple in color?
Cavernous
What disease is associated with persistence of vascular plexus around the cephalic portion of the neural tube and is associated with a port wine stain?
Sturge-Weber Angiomatosis
What is the scientific name of port wine stains?
Nevus Flammeus
What nerve is associated with Sturge-Weber Angiomatosis?
One/more segments of the trigeminal nerve
What nerve is associated with risk for full symptoms of Sturge-Weber Angiomatosis?
Ophthalmic branch
Besides Nevus Flammeus, what other symptom presents in Sturge-Weber Angiomatosis?
Leptomeningeal angiomas
In addition to other symptoms, which disease is associated with convulsive disorders, mental retardation, contralateral hemiplagia and hypervascular changes in ipsilateral intraoral mucosa?
Sturge-Weber Angiomatosis
What disease appears as “frog eggs” or “tapioca pudding” and is frequently found in the mouth?
Cavernous Lymphangiomas
What pathology is associated with smooth muscle benign tumors?
Leiomyoma
What is the pathology that is very rare, has a predilection for the head and neck and is a neoplasm of skeletal muscle?
Rhabdomyoma
What percentage of soft tissue sarcomas in children are Rhabdomyomas?
60%
How do primary malignancies likely spread?
Via Lymphatics
Where do malignancies typically spread from the lower body?
The lungs
How might metastasis spread past the lung?
Through Batson’s plexus
What are the first and second most common sites of metastasis of soft tissue in the mouth?
- Gingiva (50%) and 2. Tongue (25%)
When malignancies spread to soft tissues in the oral cavity, what portion spreads to soft tissue and which portion spreads to bone?
2/3 soft tissue and 1/3 into bone