Opthalmics

Question 1

T/F?

NON-STERILE products are used for instillation of the eye.

Answer 1

False

STERILE

Question 2

Name the 4 types of sterile products intended for instillation into the eye?

Answer 2

• Solutions
• Suspension
• Ointments
• Ophthalmic inserts

Question 3

What are the 5 drug classes used in the eye?

Answer 3

• anti-inflammatory
• antibiotic
• vasoconstrictors
• miotics
• mydriatics

Question 4

What parts of the eye are considered transparent media with no blood vessels? (3)

Answer 4

• cornea
• lens
• vitreous

Question 5

How are oxygen and nutrients transported to non-vascular areas throughout the eye?

Answer 5

aqueous humor

Question 6

Name the following volumes:
Tear Volume(eye moisture)-
How much volume can the eye hold-
Eye drop volume

Answer 6

Tear volume- 7 uL
Eye holds- 10 uL
Eye drop- 50-75 uL

Question 7

Ophthalmic solutions are normally packaged in multiple dose containers that contain what?

Answer 7

preservatives

Question 8

What are the 3 types of functional uses for contact lenses?

Answer 8

• corrective
• cosmetic
• therapeutic

Question 9

What are the 3 types of lenses available?

Answer 9

• soft
• hard
• rigid gas permeable

Question 10

Which type of lenses uses a hydrogel such as (HEMA- hydroxytethyl methacrylate)?

Answer 10

Soft lenses

Question 11

Transscleral iontophoresis is used under what circumstances?

Answer 11

for drug targeting to posterior segment of eye

Question 12

What are the 2 type of contact lens solution?

Answer 12

• Multi-purpose: rinsing and storage agent

- Enzymatic cleaning, disinfection, and neutralization

Question 13

vasoconstrictors?

Answer 13

remove redness in the eye (should not be used chronically)

Question 14

miotics?

Answer 14

constrict the pupil

Question 15

mydriatics?

Answer 15

dilate the pupil–> to see the back of the eye

Question 16

An eye drop contains 50-75 uL, although the eye can only hold 10uL. Where does the extra volume go?

Answer 16

drained off by nasolacrimal drainage (nose and throat)

Question 17

What is the purpose of increasing the viscosity?

Answer 17

to increase how long the contact is in contact with the eye

Question 18

_____ drugs are better absorbed in the body

Answer 18

unionized

Question 19

Of the products used for instillation which has the highest increased contact time?

Answer 19

ophthalmic inserts

Question 20

What has allowed extended wear of contact lenses due to high oxygen permeability?

Answer 20

silicone hydrogel