Capsules

Question 1

Advantages of solid dosage (5)

Answer 1

• convenient
• light weight
• tasteless
• easy identification
• long shelf life

Question 2

T/F Capsules almost always have an excipient

Answer 2

TRUE

Question 3

______ is what makes opaque color

Answer 3

titanium dioxide

Question 4

Capsules can be found in ____ or ____ gelatin shell

Answer 4

soft or hard (both contain 12-16% water)

Question 5

How is gelatin obtained?

Answer 5

by partial hydrolysis of collagen (from skin and bones of animals)

Question 6

T/F gelatin is soluble in hot water and warm gastric fluid

Answer 6

TRUE

Question 7

Do companies marketing capsule products make the capsule shells first or are they made as part of the filling process?

Answer 7

the capsule shells are made first

Question 8

__________ is very important when making the capsule shells

Answer 8

controlled temperature

Question 9

How are the 2 capsule parts brought together?

Answer 9

• sealed by colored bands of gelatin

- locking groves in the shell wall

Question 10

000 and 5, which is larger?

Answer 10

000 is the largest–> the larger the number the smaller the capsule

Question 11

In order to determine if a formulation will fit in a capsule?

Answer 11

you need the bulk density of the formulation

Question 12

What 3 things help with the flow rate of capsules?

Answer 12

• diluent
• glidant
• lubricant

Question 13

magnesium stearate is an example of?

Answer 13

lubricant–> it is hydrophobic

Question 14

What is the goal of mixing and blending of capsules?

Answer 14

to produce a homogeneous mass

Question 15

What is the purpose of making 5-10% extra powder?When is this not okay?

Answer 15

some may be lost; when making control substances

Question 16

rotary die process

Answer 16

liquid gelatin formed into two continuous ribbons