OPMH Teaching (ppt as missed) Flashcards

1
Q

Define delirium

A
  • sometimes called ‘acute confusional state
  • common clinical syndrome characterised by disturbed consciousness, cognitive function or perception
  • Has an acute onset and fluctuating course.
  • It usually develops over 1–2days.
  • It is a serious condition that is associated with poor outcomes. However, it can be prevented and treated if dealt with urgently.
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2
Q

Signs/symptoms of delirium

A
  • Impaired consciousness and attention
  • Rapid onset
  • Psychotic symptoms; usually visual hallucinations, transient delusions
  • Disturbance of the sleep–wake cycle
  • Emotional disturbance - depression, anxiety perplexity
  • Disturbance of motor activity - both under and over-activity.
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3
Q

When does delirium often occur?

A
  • General medical wards
  • After hip fracture
  • After stroke
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4
Q

Three types of delirium

A
  • Hyperactive - heightened arousal, restless, agitated and aggressive (least common)
  • Hypoactive - withdrawn, quiet and sleepy, underdiagnosed and misdiagnosed as depression. Longer hospital stay in this variant
  • Mixed
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5
Q

Other 3 types of delirium

A
  • Delirium superimposed on dementia - common as dementia is strong RF
  • Persistent - several weeks-months
  • Subsyndromal delirium (SSD) - one or more but not all symptoms of delirium. Associated with lower cognitive function, increased hospital stay and decreased post discharge survival at 12 months
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6
Q

Define dementia

A
  • Range of cognitive and behavioural symptoms that can include memory loss, problems with reasoning and communication and change in personality
  • And a reduction in a person’s ability to carry out daily activities, such as shopping, washing, dressing and cooking.
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7
Q

ICD 10 dementia diagnosis features

A
  • 6 months or more.
  • A decline in memory.
  • A decline in other cognitive abilities.
  • Preserved awareness of the environment (i.e. absence of clouding of consciousness).
  • A decline in emotional control, motivation or changes in social behaviour.
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8
Q

Alzheimers disease - parietotemporal features

A
  • Aphasia
  • Agnosia
  • Apraxia
  • Apathy
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9
Q

Frontal Alzheimers disease symptoms

A
  • Irritability
  • Disinhibition
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10
Q

Scoring vascular dementia

A

Hachinski ischaemic score 1974

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11
Q

Hachinski ischaemic score

A
  • Abrupt onset (2)
  • Stepwise deterioration (1)
  • Fluctuating (2)
  • Nocturnal confusion (1)
  • Preserved personality (1)
  • Depression (1)
  • Somatic complaints (1) - excessive thoughts about symptoms eg pain
  • Emotional incontinence (1)
  • RF for vascular disease (eg hypertension(1), stroke(2), atherosclerosis(1))
  • Focal neurological symptoms (2) or signs (2)

Score of 4 = AD or other dementia (non vascular)
Score of 7.= VaD

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12
Q

Dementia with Lewy Bodies core features - two needed for probable diagnosis, one needed for possible

A
  • A. Fluctuating cognition with pronounced variations in attention and alertness.
  • B. Recurrent visual hallucinations which are typically well- formed and detailed.
  • C. Spontaneous motor features of parkinsonism.
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13
Q

Supportive features of Lewy Body dementia

A
  • Repeated falls
  • Syncope
  • Transient LOC
  • Neuroleptic sensitivity
  • Systematized delusions
  • Hallucinations in other modalities
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14
Q

Investigations for someone presenting with mood disturbance

A
  • Routine bloods - FBC, LFT, U&E, glucose, lipids, B12, folate, calcium, phosphate, magnesium
  • Urine dip for blood
  • ECG
  • CXR
  • CT head
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15
Q

Confusion assessment method (CAM) for delirium

A
  1. Acute onset and fluctuating
  2. Inattention
  3. Disorganised thinking
  4. Altered level of consciousness

If features 1 and 2 and either 3 OR 4 are present = CAM positive

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16
Q

4AT for delirium

A
  1. Alertness
  2. AMT4 - age, DOB, place, current year
  3. Attention - months of year backwards
  4. Acute change or fluctuating course

4 and above = ?delirium +/- cognitive impairment
1-3 = possible cognitive impairment
0 = unlikely

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17
Q

What does NICE recommend as cognitive testing?

A
  • 10 point cognitive screener (10-CS)
  • 6 item cognitive impairment test (6CIT)
  • 6 item screener
  • Memory impairment screen (MIS)
  • Mini-cog
  • Test your memory (TYM)
18
Q

Questionaires for supplementing cognitive assessments

A
  • IQCODE - informant questionaire on cognitive decline in elderly - from someone who knows them well
  • FAQ - functional activities questionaire
19
Q

MMSE biases

A
  • Baseline education level –> ceiling and floor effect
  • Language
  • Cultural barriers
20
Q

Cut off for MMSE

A

Total is out of 30
<24 = cut off

21
Q

Addenbrookes cognitive examination (ACE)

A
  • Total /100
  • MMSE + executive function, viuospatial, complex language
  • 5 domains - attention, memory, verbal fluency, language and visuospatial abilities
  • Cut offs are <88 or <82
22
Q

MOCA

A
  • 30 points
  • Orientation, memory, language, attention, executive function
  • 10 minutes
  • Detects early AD and mild cognitive impairment
  • Cut off <26
23
Q

Other scales for cognition/dementia

A
  • Mattis Dementia rating scale
  • Cambridge cognitive examination revised (CAM-COG)
  • Azheimers disease assessment scale (ADAS-Cog)
  • FAB - frontal assessment battery
24
Q

Abbey pain scale for dementia patients

A
  • Vocalisation
  • Facial expression
  • Body language
  • Physiological changes
  • Physical changes
  • Marking is 0-3+
25
Q

Non-pharmacological (environment) measures do’s and don’ts for delirium

A
26
Q

Management of delirium caused by substance withdrawal or seizures

A
  • Benzodiazepines
  • BUT do not used for non-withdrawal delirium
27
Q

Antipsychotics for delirium

A
  • Avoid in those with dementia + Lewy bodies and parkinsons
  • Limit to use in severe behavioural disturbance that place or others are at risk and non-pharm have failed
28
Q

Antipsychotics for delirium examples

A
  • Haloperidol or Olanzapine for short term (<1 week)
29
Q

follow up for delirium

A
  • Refer to memory service or CMHT for older people for further assessment and f/u
  • Could be first presentation of dementia or severe illness
  • Consider support and counselling
30
Q

What to do if patient lacks capacity?

A
  • Treat in their best interests under mental capacity act (MCA)
  • Or in some cases mental health act (MHA)
31
Q

Menta capacity act principles

A
  1. Presume capacity
  2. Individuals being supported to make their own decisions
  3. Can be an unwise decision
  4. Best interests
  5. Least restrictive option
32
Q

2 part test of capacity

A
  • Diagnostic - impairment of functioning of the brain/mind
  • Capacity - understand, retain, weigh-up, communicate back
33
Q

DOLS - deprivation of liberty safeguards

A
  • Part of MCA
  • Ensure people in care homes and hopsitals are looked after in a way that does not inappropriately restrict freedom
  • Must follow process if they believe it is in their best interests to deprive a person of their liberty in order to provide a care plan
34
Q

MHA vs MCA

A
  • MHA does not cover treating physical illness
  • Unless cause or direct consequence of MH illness
  • Delirium may need to be detained under MHA for period of assessment and treatment
35
Q

Commonly used sections of mental health act

A
  • Nurses holding power for up to 6 hrs on a patient already in hospital informally being treated for mental disorder
  • Not renewable - period of assessment/detention cannot be restarted/renewed
  • No right to appeal to tribunal
  • Cannot be used in A&E
  • Drs holding power of 73hrs for a full MHA assessment
36
Q

Police holding power MHA

A
  • Allows for individual to be detained for up to max period of 24hrs
  • Clock starts ticking when an individual arrives at a place of safety
37
Q

Management of dementia - general

A

Bio, psycho, social
Biological:
* optimise vascular RF
* possible role Ach esterase inhibitors for AD +/- memantine
* Treat any psych co-morbid (eg SSRI)
* Advice re alcohol

Psychological:
* Cognitive stimulation therapy
* CBT depression
* Living well with dementia
* Reality orientation, reminiscence therapy

Social:
* Ensuring social support - carers, meals on wheels, day centre
* Compliance aids for meds
* OT assessment
* Alzheimers society - info and carer assessment
* Support for carers - carers groups etc

38
Q

Ach esterase inhibitors available for AD

A
  • Donepezil
  • Galantine
  • Rivastigmine

Stopped if no improvement after 3-4 months

39
Q

Side effects of Ach esterase inhibitors for AD

A
  • Headache
  • Nausea + vomotting
  • Weight loss
  • Diarrhoea
  • Anorexia
40
Q

When is memantine used?

A
  • Moderate to severe Alzheimers
  • If unable to tolerate Ach esterase inhibitors
  • NMDA antagonist - affects glutamate transmisison
41
Q

Risk assessment for those with dementia

A
  • Ask about situations where the patients have put themselves at risk and how often this has happened
  • Eg getting locked out of house, getting lost, driving, leaving cooker on
42
Q

Management depression

A
  • Biopsychosocial
  • Antidepressants
  • Psychological - CBT, psychotherapy
  • Social - social prescribing