Opioid Agonists Flashcards

1
Q

MOA: ALL

A

Opioid Receptor Agonist

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2
Q

Dose: Morphine

A

0.1-1 mg/kg IV

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3
Q

VD: Morphine

A

3-5

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4
Q

Half Life: Morphine

A

2-3 hours

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5
Q

Dose: Meperidine (Demerol)

A

2.5-5 mg/kg IV

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6
Q

VD: Meperidine (Demerol)

A

3-5

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7
Q

Half Life: Meperidine (Demerol)

A

3-5 hours

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8
Q

Dose: Fentanyl

A

Induction: 1-2 mcg/kg
gtt: 1-3 mcg/kg/hr

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9
Q

VD: Fentanyl

A

2-8

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10
Q

Half Life: Fantanyl

A

1-5 hours

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11
Q

Context Sensitive Half Time: Fentanyl

A

4 hours

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12
Q

Dose: Sufentanil

A

Induction: 1-2 mcg/kg; then 10-50 mcg PRN
Anesthesia: 8-30 mcg then 25-30 mcg

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13
Q

VD: Sufentanil

A

2.5-3

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14
Q

Half Life: Sufentanil

A

3 hours

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15
Q

Context Sensitive Half Time: Sufentanil

A

30 minutes

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16
Q

Dose: Alfentanil

A

Loading Dose: 8-100 mcg/kg

Maintenance: 0.5-3 mcg/kg/min

17
Q

VD: Alfentanil

A

0.4-1

18
Q

Half Life: Alfentanil

A

1-2 hours

19
Q

Context Sensitive Half Time: Alfentanil

A

60 minutes

20
Q

Dose: Remifentanil

A

Loading: 1 mcg/kg

Intra-Op: 0.5-3 mcg/kg/min

21
Q

VD: Remifentanil

A

0.3-0.4

22
Q

Half Life: Remifentanil

A

<10 min

23
Q

Context Sensitive Half Time: Remifentanil

A

4 minutes

24
Q

Naloxone (Narcan)

A

MOA: Competitive antagonism of opiate receptors
Dose: 0.4 mg (10 mcg/kg) may repeat q2-3 min
Half Life: 60-90 minutes