Antiemetic Medications Flashcards
1
Q
MOA: Ondansetron (Zofran)
A
Selectively blocks serotonin 5-HT3 receptors peripherally (Abd vagal afferents) & centrally (CTZ)
2
Q
Dose: Ondansetron (Zofran)
A
Periop - 4 mg (on emergence)
Postop - IV/PO 4 mg
3
Q
MOA: Metoclopramide (Reglan)
A
Dopamine 2 receptor antagonist, Blocks DA receptors at the CTZ; stimulates upper GI motility and ↑ gastric emptying
4
Q
Dose: Metoclopramide (Reglan)
A
Preop: 10-20 mg IV over 3-5min to decrease gastric fluid
Postop: 10mg at end of procedure for NV
5
Q
MOA: Promethazine (Phenergan)
A
H1 receptor antagonist, anticholinergic, a antagonist, dopaminergic antagonist (CTZ)
6
Q
Dose: Promethazine (Phenergan)
A
12.5-25 mg
