Opiod Agonists and Antagonists Flashcards
1
Q
Opioid Toxicity triad
A
- pinpoint pupils
- respiratory depression
- coma
2
Q
Which opiod agonist receptor is linked with physical dependence?
A
- MU receptor
3
Q
What is produced when the kappa receptor is activated?
A
- sedation
- Deceased GI motility
- resp depression
4
Q
What is produced when MU receptor are activated?
A
- Resp depression
- Sedation
-euphoira
5
Q
What is used to reverse respiratory depression cause by opiods?
A
- Narcan ( Nalaxone)
6
Q
What happens if anticholinergics or antihistamines are given with opiod agonsits?
A
- increase constipation and urinary retention
7
Q
How should opiods be discontinued ?
A
withdraw slowly and taper over a period of 3 days
8
Q
What is codeine used for?
A
- mild to moderate pain and cough suppression
9
Q
Therapeutic use for agonist- antagonists
A
- pain relief
- treatment of opioid dependence
- labor pain
10
Q
Signs of abstinence syndrome?
A
-Vomiting
- fever
- hypertension
- cramping
11
Q
When does abstince syndrome occur?
A
When agonist-antagoinst are given to pt dependent on opiods
12
Q
Adverse effects of opiod antagonists?
A
-Tachycardia
- tachypnea
- abstince syndrome
