Intranasal Cyancobalamin ( B12)

Question 1

Vitamin B12 generic name ?

Answer 1

Cyanocobalamin

Question 2

Cyancobalamin B12 expected pharm action

Answer 2

-necessary to convert folic acid from inactive form to active form
- all cells rely on folic acid for DNA production
- Vitamin B12 deficiency can result in a megoblastic anemia and can cause dysthymias and heart failure
- Neuro damage, numbness, tingling in extremities

Question 3

Cyancobalamin B12 therapeutic uses?

Answer 3

-treatment of vitamin B12 deficiency and megaloblastic anemia related to B12 deficiency

Question 4

Cyancobalamin B12 Complications?

Answer 4

-Hypokalemia
-Gi distress ( N/V,D)
-Dyspepsia (abdominal pain)

Question 5

Cyancobalamin B12 contraindications/ precautions?

Answer 5

-Pregnancy and lactation
-moderate B12 deficient can be managed by B12 alone
-Severe should be treated by B12 and folic acid

Question 6

Cyancobalamin B12 Interactions?

Answer 6

-masks manifestations of B12 deficiency with concurrent admin of folic acid

Question 7

Cyancobalamin B12 pt education?

Answer 7

Avoid eating and drinking hot beverages 1hr before and after administration

Question 8

Cyancobalamin B12 Dosage?

Answer 8

2.4 mcg a day