Ophthalmology Clinical Correlation Flashcards
How many people get cataracts?
Everyone
Age related
What are the big three eye diseases?
Cataracts
Macular degeneration
Glaucoma
What are indications of cataract surgery?
Severe visual loss
Functional needs
Driving
What is macular degeneration?
Age related, over 50
Central vision loss
Two types:
Dry
Wet
What do you see in dry macular degeneration?
Pigment changes
Drusen
What is exudate (dry) macular degeneration?
Defects develop in deep layers of the retina
Growth of blood vessels under the retina, edema, and finally hemmorhage
Dry can become wet
Scarring can happen and blinding
How do you treat macular degeneration?
Stop smoking
Dry: eat veges, nutrition, AREDS (age related eye disease study) supplements,
Wet: above, plus conventional laser, photodynamic therapy. Anti vegf drugs (vessel formation)
What are some causes and symptoms of glaucoma?
Increased intercranial pressure causes optic nerve loss
Any age, mainly after 40
What are the two main types of glaucoma?
Open angle Closed angle (narrow)
What is the treatment of glaucoma?
Lower eye pressure
Medical, surgical, laser
What is the place where the iris meets the eye?
The angle
What happens on open angle glaucoma?
Trabecular mesh work leading to schlemms canal is the main blockage
Thicker and less open with age
What allows you to quantify optic nerve tissue?
Optical coherence tomography
What is acute/narrow angle glaucoma and what is a main symptom?
Painful Acute emergency Loss of vision Feels hard Nausea Iris is pushed up against the canal
What are symptoms of narrow angle glaucoma?
Pain, photophobia, blur, halo around lights
Corneal edema
How do you treat closed angle glaucoma?
Pilocarpine (know!!!)
Acetazolamide
How do you treat closed angle glaucoma per neatly?
Laser iridotomy
What is diabetic retinopathy like?
Mild to severe
Slow progressive
Can cause total blindness
What is the pathophysiology of diabetic retinopathy?
Alterations in pericytes Micro-occlusions Retinal ischemia VEGF upregulation Angiogenesis Hemorrhage Organization into scar tissue Traction (detachment)
What are the two main kinds of diabetic retinopathy?
Nonprolierative diabetic retinopathy (NPDR)
Proliferative diabetic retinopathy (PDR)