Gustatory Pathways And Gustation Flashcards
(38 cards)
What is conditioned taste aversion?
Pairing of a non toxic food with a toxic stimulus
Problematic in chemo patients because it changes taste
What are the five tastants and their benefits?
Sweet-nutrition Sour-Hydrogen Salty-sodium Bitter-toxic Umami-nutrition
Is taste special sense?
Yes
Traditional
The receptor is not on the primary afferent neuron
How many taste receptors are on each taste bud?
50-150
Each receptor cell does one of the five taste
How often do taste receptor cells turn over?
Once every 10days
What is gustatory transduction?
Transduction of taste
Each taste is kinda different
What is the process of gustatory transduction for bitter, sweet, and umami?
- Receptor activation
- G protein (Gustducin)
- 2nd messenger system
- Depolarization
- Open VG Ca channels or release Ca intracellularly
- ATP
What is the gustatory transduction pathway for sour and sweet and why is it different?
It is different because ions are being perceived
- Receptor activation
- H ion closes K channel, Na opens a channel
- Same as previous
- Depolarization
- Voltage gated Ca or intracellular
- Serotonin
What is a defect is the olfactory system called?
-osmia
What is a defect in the gustatory system called?
-geusia
What a complete absence of smell of taste called?
Anosmia or ageusia
What is reduced perception of smell and taste called?
Hyposmia or hypogeusia
What is increased perception of smell called?
Hyperosmia
What is distortion of perversion of smell or taste called?
Dysosmia and dysgeusia
What is extremely unpleasant perception of smell or taste called?
Cacosmia and cacogeusia
What is it called when they know there is a stimulus there but they can’t characterize it?
Agnosia
What is a peripheral defect of smell/taste?
Chemicals cannot reach the receptors
Olfaction-Too much mucus
Inflammation
Foreign body
Gustation - dryness, too thick (cystic fibrosis)
What is a neuroepithelial defect for smell/taste?
Damage or absence of receptor cells or damage to any process of the transduction mechanism
Olfaction- head trauma, many drugs
Gustation - burn, drugs
What is a central defect to smell/taste?
Damage of malfunction in any of the central pathways
Hallucinations and loss of discrimination are usually of central origin
Alzheimer’s
What are taste bud cells?
Modified epithelial cells
What is chemesthesis?
Pain from a chemical
Trigeminal
What serves the posterior tongue?
Glossopharyngeal nerve
Taste, pressure, temp
What serves the taste buds on the larynx and epiglottis?
The vagus nerve
What serves taste on the anterior 2/3s of the tongue?
Facial nerve