Embryology Of The Face And Palate Flashcards

0
Q

What are the three prominences that will transform into the face?

A

Frontonasal
Maxillary
Mandibular

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1
Q

What are the maxillary and mandibular prominences from?

A

The first pharyngeal (brachial) arch

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2
Q

What are placodes and what facial structures are derived from them?

A

A facial primordia
Ectodermal thickenings with neurological potential that appear in pairs on the developing head. Contribute components to the special senses

Three of them:
Lens
Otic (inner ear)
Nasal (nasal cavity and part of upper lip)

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3
Q

What are the facial prominences derived from?

A

Neural crest cells

Migrate into the pharyngeal arches

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4
Q

What is the frontonasal prominence?

A

Mesenchyme ventral to brain vesicles

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5
Q

Where is the maxillary prominence from?

A

Extension of the first pharyngeal arch

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6
Q

Where is the mandibular prominence from?

A

First pharyngeal arch mesenchyme

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7
Q

What is the stomodeum?

A

Depression in the ectoderm surrounded by five facial prominences. Future site of mouth

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8
Q

What does the surface ectoderm of the stomodeum form?

A

The floor of the oropharyngeal (buccopharyngeal) membrane

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9
Q

When does the oropharyngeal membrane break down and what does it form and where was it?

A

Day 24

Opens the primitive gut to the amniotic cavity

Membrane was located at the junction of the anterior 2/3 and posterior 1/3 of the tongue

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10
Q

Where do the facial primordia mostly migrate?

A

To the midline

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11
Q

What does the fromtonasal prominence form?

A

Midline structures of the face

  • forehead, dorsal aspect of the nose
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12
Q

What do the medial and lateral nasal prominences form?

A

As elevations on the frontal nasal prominences around the developing nasal placodes/pits

Medial - migrate medially, fuse and form the inter maxillary segment, contributing to the midline of the nose and part of the nasal septum, philtrum of the upper lip, per maxillary part of the maxilla, and primary palate

Lateral - migrate to form the sides of the nose

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13
Q

What happens as the nasal pits deepen?

A

They move midline and fuse into the intermaxillary segment

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14
Q

What week does the nose obtain a more human shape?

A

8

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15
Q

What happens at the line of the maxillary and frontonasal prominence?

A

Surface ectoderm makes a cord in the nasolacrimal groove, undergoes apoptosis and becomes the lacrimal duct

16
Q

What happens if the lacrimal duct does not open?

A

Chapped eyes
Infections
Will have to open

17
Q

What is the progression of nasal placodes?

A

4.5 weeks nasal placodes - 6 weeks nasal pits - 7 weeks nasal sacs

18
Q

What is the nasal sac?

A

Surface ectoderm

19
Q

What is the oronasal membrane?

A

Separates the oral and nasal cavity

Breaks by apoptosis

20
Q

What does the surface ectoderm of the nasal placodes form?

A

Diff into neural ectoderm and forms hair cells and nerves that go to the old
Factory bulb

21
Q

What is choanal atresia?

A

Failure of the nasal cavity to open

22
Q

What is the critical period of palate development?

A

Week 6 to the beginning of week 9

23
Q

Where does the palate derive from?

A

Primary palate from the intermaxillary segment

Secondary palate from the palatine shelves of the maxillary prominences

24
Q

Where does the incisive foramen mark?

A

Where the primary and secondary palates come together

25
Q

What forms the palatine shelves?

A

He secondary palate

26
Q

What are some anterior defects that are congenital abnormalities of the lip and palate?

A

Due to failure of fusion of the maxillary prominences with the fused medial nasal prominences

Cleft involving upper lip, alveolar part of the maxillar and primary palate

27
Q

What are some causes of posterior defects of the palate?

A

Failure of the fusion of the palatine shelves with one another, nasal septum and with the posterior margin of the primary palate.

Involve hard and soft palate

28
Q

What are facial features of fetal alcohol syndrome?

A

Indistinct philtrum

Flat mid face

Small jaws

29
Q

Do you have sinuses at birth?

A

No. Maybe ethmodial

30
Q

What helps jaw development?

A

Chewing