Ondansetron Hydrochloride Flashcards
Drug classification
Antiemetic
Trade name
Zofran
Actions
Blocks the serotonin receptors in the chemoreceptor trigger zone in the stomach and small intestines
Indication
Nausea and/or vomiting
Contraindication
None
Adverse effects - cardiovascular
Dysrhythmias
Adverse effects - respiratory (2)
Depression
Hypoxia
Adverse effects - neurological (4)
Dizziness
Fatigue
Headache
Sedation
Administration
4 mg Orally - with disintegrating tablets
4 mg IV or IM - maximum dose is 4 mg all routes
Precaution
When administering disintegrating tablets, peel the backing off the blister pack
Rationale
If you try to push the tablet through the foil, you can break the tablet
Note
Doesn’t cause extrapyramidal effects
In Los Angeles county may not be used to prevent nausea and or vomiting only to treat existing