Dopamine Flashcards
Drug classification
Sympathomimetic agent (catecholamine)
Trade name
Intropin
Actions – low dose (2)
- Dilated renal and mesenteric arteries by stimulating dopaminergic receptors
- May decrease blood pressure due to vasodilation
Low dose dosage
1-4 mcgm/kg/min
Actions – moderate dose (2)
- Increases inotropy without increasing chronotropy
2. Increases blood pressure by stimulating beta-1 receptors
Moderate dose dosage
5-10 mcgm/kg/min
Actions - high dose (3)
- Causes vasoconstriction by stimulating alpha receptors
- Increases inotropy and chronotropy by stimulating beta-1 receptors
- Increases blood pressure by stimulating alpha and beta-1 receptors
High dose dosage
> 10-20 mcgm/kg/min
Contraindication (2)
- Hypovolemia
2. Tachydysrhythmias
Adverse effects - cardiovascular (6)
Tachycardia Hypertension Hypotension Chest pain Ventricular irritability Vasoconstriction
Adverse effect - respiratory
Dyspnea
Adverse effect - gastrointestinal
Nausea/vomiting
Administration
Add 400mg to 500mL of NS as an IVPB
Start at 30 mcgtts/minute. Titrate to BP of 90-100 systolic and signs of adequate perfusion or to a maximum of 120 mcgtts/min
Pediatrics
Add 6 mg/kg to 100mL NS as an IVPB
Start at 10 mcgtts/minutes. Titrate to a sign of adequate perfusion or to a maximum of 20 mcgtts/minute
Onset
5 minutes