Ondansetron

Question 1

Ondansetron Intro

“Head blocks on…”

Answer 1

• Anti-nauseant and anti-emetic
• Selective 5-HT3 receptor antagonist blocking serotonin centrally in the chemoreceptor trigger zone and peripherally on Vagus nerve terminals.
• Onset of action up to 30 minutes

Question 2

3 Ondansetron Indications

Answer 2

• Moderate to severe nausea
• Active vomiting
• Prophylaxis for eye and spinal injuries

Question 3

2 Ondansetron Contraindications

Answer 3

• Paediatrics less than 2 years old
• Hypersensitivity

Question 4

2 Ondansetron Precautions / Notes

Answer 4

• Oral wafer is the preferred method of administration for ALL patients unless actively vomiting.
• Administer IV Ondansetron slowly over 2 minutes (neat or diluted) to prevent blurred vision and dizziness.

Question 5

5 Ondansetron Special Considerations (Side Effects)

Answer 5

• Headache
• Malaise/fatigue
• Drowsiness
• Dizziness
• Rash/allergic reaction

Question 6

Ondansetron Presentation

Answer 6

4mg wafer
4mg in 2mL vial