Amiodarone

Question 1

Amiodarone Overview

Answer 1

• Amiodarone is a Class III antidysrhythmic agent that prolongs the action potential duration and hence the refractory period of atrial, nodal and ventricular tissue, thereby giving a very broad spectrum of activity.
• Immediate onset, peak <10min, duration 30-60mins

Question 2

Amiodarone Presentation

Answer 2

150mg in 3ml

Question 3

Amiodarone Indications

Answer 3

Cardiac Arrest with persistent/shock resistant Ventricular Fibrillation/pulseless Ventricular Tachycardia, post 3rd shock

Question 4

Amiodarone Contras

Answer 4

• No contraindications in cardiac arrest
• Not compatible with Saline (if infusion dose is advocated by a specifically authorised person)

Question 5

9 Amiodarone Special Considerations (Side Effects)

Answer 5

Bradycardia
Hypotension
Polymorphic tachycardias
Nausea
Tremor
Dizziness
Paraesthesia
Headaches
Phlebitis

Question 6

Amiodarone Precautions / Notes

Answer 6

• Heart failure
• Thyroid dysfunction
• Amiodarone is only indicated for shock resistant or recurrent VF / pulseless VT

MUST NOT be diluted into NaCl (e.g. if infusion doses are advised via ASMA / CSP)