Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

DOCTOR OF DENTAL MEDICINE 3 FIRST SEM MIDTERMS > ONCOLOGY PRELIMS > Flashcards

ONCOLOGY PRELIMS Flashcards

1
Q

how does biologic therapy work?

A

induce immune system to attack cancer cells and make cancer cell easier for the body to revognize

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

main treatment for leukemia and aplastic anemia is?

A

bone marrow transplant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

treatment of choice for brain cancer, bladder, melanoma and testicular cancer

A

vinblastine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

is also called a tumor supressor gene

A

P53

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

the main therapy for metastatic cancers

A

chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

attacks negatively charged sites of the DNA

A

alkylating agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

inhibits topoisomerase by forming complex with the enzyme and DNA

A

anthracyclines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

causes cancer by forming free oxygen radicals

A

anthracyclines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

meditation, massage, quack doctors, acupuncture are examples of

A

CAM II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CAM I are

A

ingested or injected herbals, vitamins,organics, chemicals, and diets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

works by blocking the actions of different hormones to stop cancer from growing

A

hormone therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

a novel cancer treatment which works by exposing a photosensitizing drug to specific wavelengths of light to kill cancer cells

A

PHOTODYNAMIC THERAPY PDT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

biopsy is used for

A

diagnostic purposes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cancer vaccine or vaccine therapies mechanism

A

teaches the immune system to attack and destroy cancer cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

cancer vaccine is similar to

A

biologic therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

bind with high affinity to the microtubules and inhibit their normal functions

A

taxanes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

treatment choice for breast and lung cancer

A

Vinorelbine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

deals with tumors including the origin development and diagnosis and treatment of benign and malignant neoplasm

A

oncology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is a neoplasm

A

new growth, uncontrolled growth of abnormal tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

2 general characteristics of a neoplams

A

behave as parasite and autonomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

tumor could be due to?

A

malformation, reparative process, an inflammation, and neoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

2 types of neoplasm

A

benign and malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

an important feature of malignant tumor is the ability to

A

metastasize

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

it is the transfer of cancer cells to other parts of the body

A

metastasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
it is the capability to induce cancer
oncogenicity
26
any gene that is a causative factor in the initiation of cancerous growth
27
cell proliferation growth stes
regeneration, hyperplasia, metaplasia, dysplasia, anaplasia
28
criterias by which a diagnosis is made in primary lesions
anaplasia and evidence of invasion
29
variable in size and shape
pleomorphism
30
adaptive substitution by one type of adult or fully differentiated cell to another
metaplasia
31
the main cause of metaplasia is
vitamin A deficiency
32
T OR F: metaplasia of the connective tissue is reversible
F= it is irreversible because it causes permanent damage to the site of injury
33
four characteristics of dysplasia
loss of uniformity of the individual cells loss of architectural orientation pleomorphism hyperchromatic nuclei
34
cells of benign or malignant neoplasm
oncocytes
35
quantitative increas ein cells
hyperplasia
36
ability to regrow lost body parts
regeneration
37
localized tumors
benign tumors
38
carcinomas are malignant tumors of?
epithelial tissues
39
sarcomas are malignant tumors of ?
mesenchymal tissues
40
chondroma
benign tumor of the cartiliganous tissue
41
parenchyma are
the cells of a neoplasm
42
it is the supporting layer of connective tissue, blood vessels, and lymphatics of the parenchyma
stroma
43
fleshy tumor
sarcoma
44
firm tumor
desmoplasia/ schirrous tumor
45
very little fibrous stroma soft and fleshy
sarcoma
46
t or f: neoplastic cells divide more rapidly than normal cell
tama tih
47
pathway wherein reimplantation of cancer happens on distant sites
seeding of cancer
48
breast cancer pathway
lymphatic drainage
49
due to unsterilized instruments
transplantation
50
pass through capillaries
blood vessels invasion
51
mechanisms of invasion
a. laminin molecule 2. attachment of tumor cells in the laminin molecule 3. attachment of the tumor cell to the basement membrane via the laminin molecule 4. dissolution 5. invasion
52
enumerate the epithelial odontogenic tumor (5)
1. ameloblastoma 2. calcifying epithelial odontogenic tumor 3. adenomatoid odontogenic tumor 4.squamous odontogenic tumor 5. clear cell odontogenic tumor
53
located in mandibular molar areas
ameloblastoma
54
it is the soft tissue counterpart of ameloblastoma
extraosseous peripheral ameloblastoma
55
clinical features of ameloblastoma
- benign non agressive course - asymptomatic jaw expansion -tooth movement and malocclusion - affects impacted posterior teeth
56
t or f: ameloblastomas are only unilocular
false: both multi and unilocular
57
polarization of cells around proliferating rest, budding of tumor cells, loosely arranged cells in the middle
ameloblastoma
58
multicystic lesions:surgical excision unicystic lesion
enucleation
59
pinborg tumor is also known ans
calcifying epithelial odontogenic tumor
60
etiology of CEOT
unknown
61
snow driven appearance
CEOT
62
can be mixed lucent and opaque
ceot
63
the radiopaque foci in CEOT represents
calcified islands
64
histopathological salient feature of CEOT is the presence of
LIESEGANG RINGSB
65
T OR F: anaplasia can be seen in CEOT
true
66
molar ramus region
ceot
67
presenec of enameloid islands
adenomatoid odontogenic tumor
68
adenomatoid odontogenic tumor is also known as
2/3 tumor
69
location of adenomatoid odontogenic tumor
anterior portion of the maxilla
70
divergence of roots between anterior teeth
AOT
71
rosettes or duct like structures are salient features of
adenomatoid odontogenic tumor
72
differential diagnosis of AOT
dentigerous cyst, lateral root cyst, ceot, calcifying odontogenic cell
73
the only malignant epithelial odontogenic tumor is
clear cell odontogenic tumor
74
location of squamous odontogenic tumor
anterior maxilla nd posterior mandible
75
etiology og squamous odontogenic tumor
neoplastic transformation of the epithelial rests of malassez
76
anterior portion of the maxilla
aot
77
the presence of enameloid materials scattered
aot
78
well circumscribed with semilunar lesions in the roots
Squamous odonogenic tumore
79
found more in women over 60 yrs of age
clear cell odontogenic tumor
80
locally aggressive and metastases to lungs and regional lymph nodes
ccot
81
treatment for CCOT
en bloc resection
82
poor prognosis
CCOT
83
enumerate the mesenchymal odontogenic tumor
odontogenic myxoma, central odontogenic fibroma, cementifying fibroma, cementoblastoma, periapical cemental dysplasia
84
there is cortical expansion rather than perforation
odontogenic myxoma
85
female around 40 years old are effected
cementifying fibroma
86
similar to ameloblastoma
central odontogenic fibroma
87
treatment for cementifying odontogenic fibroma is
enucleation or excision
88
histopathology shows globules surrounded by eosinophilic cementoid and cementoblasts
cementifying fibroma
89
treatment of cementifying fibroma
sacrifice affected too throigh enucleation and excision
90
biopsy is needed in this tumor
florid osseous dysplasia/pagets disease
91
why is biopsy needed in pagets disease
to rule out serum alkaline phosphate
92
treatment for florid osseous dysplasia
no treatment is necessary
93
hamartoma rather than a neoplasm
odontoma
94
odontoma is common in what age group
children and young adults
95
compound odontoma location
anterior
96
complex odontoma location
posterior
97
stages of periapical cemental dysplasia early: mature: final:
continuous wiht the PDL space mottled appearance due to bone repaire solid opaque lesionsurrounded by lucent ring
98
amorphous masses or cauliflower in appearance on a radiograph
complex odontoma
99
appearance of compund odontoma
several mature teeth in a single focus
100
presence of ghost cell keratinization
odontoma
101
there is general absence of collagen
ameloblastic fibroma, fibroodontoma
102
genes can be used to prevent blood vessels from forming thus starving tumor to death in a process called
antiangiogenesis
103
stops cancer cell multiplication and replication
vinca alkaloids
104
act by forming a complex with topoisomerase and DNA resulting in the inhibition and function of the topoisomerase enzyme
camptothecan analogs
105
most potent carcinogens
polycyclic aromatic hydrocarbonswe
106
weak carcinogens
direct acting alkylating agents
107
degrees of risk to UV
quantity of melanin on the skin and intensity of exposure

DOCTOR OF DENTAL MEDICINE 3 FIRST SEM MIDTERMS (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions